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Biomedical subjects

C R Srinivas

Publications and source records attributed to C R Srinivas.

At least 37 records · Page 2Linked to original sources

Molds in onychomycosis.

BACKGROUND: Onychomycosis is a major cause of nail dystrophy. The causative organisms in onychomycosis are dermatophytes, Candida and molds. A variety of molds have been isolated from nails. METHODS: Nail scrapings and clippings were collected from 100 cases and inoculated on slants containing SDA with cycloheximide 0.5 mg/mL, chloramphenicol 0.05 mg/mL, and SDA with chloramphenicol 0.05 mg/mL. RESULTS: The culture positivity rate for molds was 22%. The predominant mold isolates were Aspergillus species (86.4%, Fusarium oxysporum (4.5%), Curvularia species (4.5%) and Penicillium species (4.5%). CONCLUSION: Primary invasion of nails by molds can cause onychomycosis.

Female↗

Footwear dermatitis.

We conducted a study to determine the prevalence and clinical patterns of footwear dermatitis, patch testing 50 patients with suspected footwear dermatitis and 30 controls with 22 allergens of a shoe series (Chemotechnique Diagnostics AB, Malmö, Sweden). The overall prevalence among contact dermatitis cases was 11.7%. The dorsa of the feet and toes were the commonest sites involved. 70% of patients showed sensitivity to footwear allergen(s), as opposed to 6.67% of controls. Potassium dichromate and colophony were the commonest sensitizers. Other sensitizers were the rubber accelerators 2-mercaptobenzothiazole (MBT) and diphenylguanidine (DPG) and a dye p-aminoazobenzene. Of the 23 patients patch tested with pieces or scrapings of footwear, only 3 showed positive reactions. We recommend that there should be primary and secondary footwear screening series to detect the responsible allergens, with the ultimate objective of providing correct nonallergenic footwear for our patients, with the help of manufacturers and research institutes.

Adolescent↗