Administration of fat emulsions with nutritional mixtures from the 3-liter delivery system in total parenteral nutrition.
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Biomedical subjects
Publications and source records attributed to C R Pennington.
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Catheter occlusion by lipid material has been associated with the use of lipid containing "all-in-one" compounded solutions during prolonged parenteral nutrition. Previous experience indicated that urokinase is ineffective in clearing such occlusions. We report five patients who developed catheter occlusion with lipid mixes; catheter patency was restored in four by the use of an ethanol solution. No complications were observed, and treatment continued uneventfully in those four subjects.
Clinical central venous thrombosis (CVT) was found to be associated with a catheter tip position in the superior vena cava (SVC), but not in the right atrium (RA), in patients receiving a standard parenteral nutrition regime in which dextrose was the sole energy source. CVT was rare with standard lipid containing three in one mixes, even when the catheter tip lay in the SVC. The reasons for this are discussed and the complications associated with catheter tip position are reviewed.
Calcified intracardiac thrombi were identified in a 23-year-old man who had received home parenteral nutrition (HPN) for 4 years on account of Crohn's disease.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.