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Biomedical subjects

C R Goldfarb

Publications and source records attributed to C R Goldfarb.

At least 37 records · Page 2Linked to original sources

Lymphocytic interstitial pneumonitis: a cause of pulmonary gallium-67 uptake in a child with acquired immunodeficiency syndrome.

Lymphocytic interstitial pneumonitis (LIP) is currently recognized as a frequent pediatric manifestation of the acquired immunodeficiency syndrome (AIDS). We report the gallium scan findings in a 3-yr-old girl with this disorder and review its clinical, radiologic, and pathologic features. LIP must be a prime consideration in the differential diagnosis of diffuse pulmonary gallium uptake in pediatric AIDS patients. Further experience will afford greater perspective on the diagnostic role that nuclear medicine will ultimately play in this disease.

Acquired Immunodeficiency Syndrome↗

The offensive wrist.

Fencing between injection of Tc-99m MDP and imaging resulted in a diffuse increase in radioactivity in the asymptomatic wrist of a right-handed fencer. Repeat study two weeks later showed normal distribution of radiopharmaceutical. At that time, the athlete was fenced into the patient waiting area between injection and scan.

Adult↗

Effect of patient positioning on liver size estimation.

Technetium sulfur colloid imaging is widely regarded as a simple, accurate technique for the evaluation of liver size. Although numerous strategies have been proposed for standardizing measurements, none has considered the possibility of a variation depending on whether the patient is imaged erect or recumbent. We imaged several patients in both positions and observed an apparent increase in the vertical length of the liver from supine to upright. We confirmed this by demonstrating a significant increase in the vertical length of both the right and left lobes in a majority of 55 patients imaged in both positions.

Hepatomegaly↗

Bone scintigraphy for neonatal osteomyelitis: simulation by extravasation of intravenous calcium.

Intravenously administered calcium gluconate has become increasingly popular in the treatment of neonatal tetany. Occasionally, extravasation results in cellulitis, leading to a clinical diagnosis of superimposed osteomyelitis. Osseous scintigraphy, as the accepted modality in the early detection of osteomyelitis, would tend to be used in this circumstance. This case illustrates a false-positive result, probably due to soft-tissue calcification.

Bone and Bones↗

Metastatic cardiac tumor demonstrated by 201thallium scan.

A patient with bronchogenic carcinoma had an electrocardiogram that was initially thought to be consistent with myocardial infarction and possible left ventricular aneurysm. A heart scan with radioactive 201thallium showed an area of sharply diminished uptake ("cold spot"); however, subsequent thoracotomy showed that this was caused by local pericardial and myocardial infiltration by tumor. This suggests a role for radioactive 201thallium in the detection of cardiac metastatic tumors.

Carcinoma, Squamous Cell↗