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Biomedical subjects

C R Conti

Publications and source records attributed to C R Conti.

At least 163 records · Page 9Linked to original sources

Risk stratification in unstable angina: how to select patients who need emergency revascularization.

Patients considered to have unstable angina have a varying prognosis depending on their clinical presentation. Prognosis can be influenced by several factors including persistent pain, transient ST segment shifts, left main coronary artery stenosis, and silent myocardial ischemia. Most patients who present with unstable angina have their symptoms controlled initially with pharmacological management. If symptoms persist, coronary angioplasty or heart surgery can be performed but morbidity and mortality is slightly higher than in patients who are stable. Patients who will benefit from early revascularization include those with persistent myocardial ischemia as manifested by spontaneous angina, spontaneous ST segment shifts on ambulatory ECG, a positive exercise test at a low cardiac workload, or a markedly positive radionuclide or cardiac ultrasound imaging test.

Angina, Unstable↗

Documentation of successful treatment of prosthetic mitral valve thrombosis with intravenous urokinase infusion for twenty-four hours.

Prosthetic valve thrombosis is a life-threatening situation requiring prompt diagnosis and treatment. Treatment has usually been surgical and has been associated with a high mortality. Thrombolytic therapy is a therapeutic alternative to surgery and has been successful in a number of cases. This report concerns the technique used to diagnose the condition, treatment strategy, and documentation of the results of therapy.

Adult↗

Brief overview of the end points of thrombolytic therapy.

In addition to mortality, several measurable end points of thrombolytic therapy have been studied. These include coronary arterial patency, left ventricular function, reocclusion, reinfarction, and bleeding complications. Current wisdom dictates that recanalization of occluded arteries in the early phases of acute myocardial infarction should be attempted to preserve viable cardiac muscle, with the ultimate goal of decreasing mortality. Unfortunately, the number of patients eligible for thrombolytic therapy far exceeds the number receiving it, despite the clear benefits that have been demonstrated.

Fibrinolytic Agents↗

Cardiac catheterization laboratories: should every hospital have one?

It is obvious that times have changed. Cardiac catheterization laboratories are everywhere. The concerns that must be addressed continually are: 1. Patient safety and quality of patient care. 2. Access to emergency hospitalization. 3. The overseeing of these laboratories. 4. Physician conflict of interest. 5. Need for the laboratory in the region In order to add a new cardiac catheterization laboratory to any region, patient need must be documented. Patient need is the only justification for the development of a new laboratory. I fail to understand how the continuing development of new laboratories will decrease costs, and am concerned that more catheterization laboratories will mean more studies of patients with borderline indications for the procedure.

Cardiac Catheterization↗