Search PubMed⌕ Search

Biomedical subjects

C R Cannon

Publications and source records attributed to C R Cannon.

At least 37 records · Page 2Linked to original sources
PubMed1996

Quantitative evaluation of fine-needle aspiration.

A protocol was developed to obtain mature lymphocytes from freshly harvested tonsils by a combination of 5-, 10-, and 20-cm3 syringes and 21-, 23-, and 27-gauge needles. The cells were then suspended in Earle's balanced salt solution and counted with an automated cell counter. Cell counts for each study group was compared as a function of needle and syringe size. The range of harvested cells was 900 to 2800 cells per cubic millimeter, allowing adequate cellular material for diagnostic purposes. The amount of negative pressure for each syringe/needle combination was measured with a manometer. Pressures ranged from -500 to -700 cm of H2O pressure. In this particular study, fine-needle aspiration with a 20-cm3 syringe and 21-gauge needle yielded the best results.

Biopsy, Needle↗
PubMed1996

Peritonsillar abscess following tonsillectomy.

Peritonsillar abscess is an unusual complication following tonsillectomy. A series of five such patients is herein reported. Proper treatment begins with the initial tonsillectomy ensuring complete removal of the tonsils. Should a late peritonsillar abscess following tonsillectomy be found, the patient may be treated with needle aspiration of the affected area plus antibiotics. Removal of the remaining tonsillar tissue and surgical capsule of the tonsil is also advocated.

Adolescent↗
PubMed1996

The efficacy of a single dose antibiotic regimen in adults undergoing tonsillectomy.

Several studies have indicated that antibiotics given for 5-7 days post-tonsillectomy are beneficial. A prospective double blind randomized study was undertaken to evaluate the efficacy of a long-acting antibiotic (Cefonicid) given prophylactically at the time of tonsillectomy. Dependent variables were percent weight loss, number of doses of pain medications required postoperatively, the number of days required to resume a normal diet, and return to work. The results of all independent tests indicated that there were no statistically significant differences between the Cefonicid group and the placebo group. The results of this study indicate that single dose prophylactic application of Cefonicid is not effective in adults undergoing tonsillectomy.

Adolescent↗
PubMed1994

Carotidynia: an unusual pain in the neck.

Described by Fay in 1927, carotidynia has not received much attention in the otolaryngology-head and neck surgery literature. This unusual entity is characterized by ipsilateral neck pain in the region of the carotid artery near its bifurcation. The differential diagnosis is extensive and includes thyroiditis, migraine headache, aneurysm of the carotid system, temporomandibular joint syndrome, giant cell arteritis, and head and neck neoplasms. A correct diagnosis is usually achieved by careful review of the history and physical examination. Laboratory studies are obtained primarily to exclude other causes. Successful treatment is most often effected with the use of nonsteroidal antiinflammatory drugs, although other treatment modalities may be needed. A series of 25 patients treated during the past 10 years is presented. The symptoms, physical findings, appropriate laboratory studies, and a treatment protocol for this uncommon entity are detailed.

Adult↗
PubMed1994

Hypothyroidism in head and neck cancer patients: experimental and clinical observations.

Damage to the thyroid gland may occur in patients undergoing treatment for head and neck neoplasms. This injury may result from damage incurred during surgery, from radiation therapy, or a combination of the two. Development of hypothyroidism is often insidious with potential harmful effects. An experimental study was performed to study the effects of hypothyroidism in pigs whose skin closely approximates that of the human. Wound tensile strength and flap necrosis were studied in the hypothyroid animal treated by surgery, radiation, and a combination of the two. The results of this study indicate that hypothyroidism alone has no significant unfavorable impact on wound tensile strengths or flap survival. When combined with preoperative radiation, however, there are statistically significant deleterious effects on both wound tensile strengths and flap survival. Histologically, collagen fibers within the wound appear shorter and thinner, which probably accounts for decreased wound tensile strengths. A clinical review of 62 head and neck cancer patients was also conducted. Within the study group, 10% of patients developed abnormally low thyroxine measurements, whereas 15% developed high thyroid-stimulating hormone levels as the only evidence of early primary hypothyroidism. Hypothyroidism was not statistically related to tumor size, nodal status, clinical staging, or treatment group (surgery alone, radiation alone, or combination surgery and radiation). A previously unreported finding is that patients who develop a second primary tumor are significantly at risk for developing hypothyroidism. All patients diagnosed with a head and neck cancer should undergo baseline thyroid function testing, including measurement of TSH, and have serial repeat testing after treatment. Thyroid function determination should be mandatory in patients undergoing oncologic salvage procedures or treatment of a second primary tumor.

Adult↗
PubMed1993

Concurrent verrucous carcinomas of the lip and buccal mucosa.

Florid oral papillomatosis presents a picture of multiple squamous papillary lesions found in the oral pharynx. Multiple risk factors associated with the development of these lesions include possible association with papilloma virus, the use of tobacco products, and chronic inflammation or irritation such as that caused by poorly fitted dentures. The major risk factor of these benign squamous lesions is the dedifferentiation into a well-differentiated verrucous carcinoma. However, treatment in the early stage of the disease is usually successful. Surgical excision has been favored as the initial approach. The use of radiotherapy for verrucous carcinoma is controversial. In numerous reported cases dedifferentiation of the tumor has produced an anaplastic squamous cell carcinoma. More recent articles, however, indicate that the risk for dedifferentiation of verrucous carcinoma due to radiotherapy may be overstated.

Aged↗
PubMed1993

Effective treatment protocol for posterior epistaxis: a 10-year experience.

Posterior epistaxis remains a serious health problem. Modification of a traditional posterior pack using a Foley catheter has proved to be an effective method of treating these sites of severe posterior bleeding. Technological advancements in the form of a PCA infuser and pulse oximetry have allowed better control of packing-associated pain and identification of potential hypoxic complications.

Analgesia, Patient-Controlled↗
PubMed1993

Functional endoscopic sinus surgery in children.

During the last decade, the usefulness of functional endoscopic sinus surgery (FESS) has been clearly demonstrated in adult patients. Several recent studies have described the use of FESS in children. Most of the patients in these earlier studies have been school age or older. This paper will examine the follow-up of 44 children treated using FESS. The children's ages ranged from 14 months to 13 years with a mean age of 54.5 months. Thirty-three of the children were less than 6 years of age with a mean age of 35.3 months. Follow-up after surgery varied from 1 to 21 months with a mean of 7.4 months. There were no major surgical or anesthetic complications noted during the initial procedure or at the follow-up debridement. Overall the children did well, with 86% showing improvement. It appears that FESS can be helpful for even young children with chronic sinusitis.

Adolescent↗
PubMed1992

Pulse oximetry monitoring in patients with nasal packing.

Pulse oximetry is a safe, effective method of monitoring for hypoxia in patients with nasal packing. It provides continuous in vivo measurements of the patients' arterial oxygenation in a non-invasive fashion based on the principles of the hemoglobin dissociation curve.

Adult↗