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Biomedical subjects

C R Blagg

Publications and source records attributed to C R Blagg.

At least 55 records · Page 3Linked to original sources

Survival with dialysis and transplantation in patients with end-stage renal disease.

We examined the survival experience of 1038 white patients with end-stage renal disease to compare transplantation with maintenance dialysis. A mathematical model was used that permitted adjustment for the confounding effects of age and morbidity at the start of treatment as well as for the year in which treatment began. For patients with all kinds of renal disease, survival was related to age and morbidity but not to the year of starting treatment. Transplantation with a graft from a living related donor was associated with significantly better survival than either transplantation with a cadaveric graft (relative risk, 0.54) or dialysis (relative risk, 0.55). No significant difference in survival was found between treatment by dialysis and by cadaveric transplantation (relative risk, 1.01). In view of this experience, the decision about whether a patient on dialysis should receive a cadaveric transplant should be based on evaluation of the differences in complications associated with the two treatments and the potential effects of these on the patient's general life style, opportunity for rehabilitation, and family and social responsibilities. Whether the use of cyclosporine will change this assessment in the future remains to be seen.

Adolescent↗

A hemodialysis orientation unit.

A separate dialysis unit was created within an existing large dialysis unit for the purpose of segregating all new hemodialysis patients into an environment that would provide optimum instruction about self-care. An educational curriculum was presented to each patient during each dialysis over the first 2 months of dialysis. Depending upon medical condition and response to the curriculum, patients were transferred either to the home hemodialysis training unit with or without a helper, to the limited care facility, or to the general dialysis area for medically unstable patients. An orientation unit not only improves patient participation in self-care, but appears to increase the number of patients interested in dialyzing at home.

Adolescent↗

Implications for health care policy. A social and demographic profile of hemodialysis patients in the United States.

Before 1973, selection of patients with end-stage renal diseases (ESRD) for treatment was necessary because of inadequate medical and financial resources. Patients were selected based partly on social worth rather than medical suitability. In 1973 ESRD patients became eligible for Medicare benefits, eliminating the financial barrier to treatment. Using data from two national surveys of hemodialysis patients in 1967 and 1978, two social and demographic profiles of patients illustrate the effect of extension of Medicare benefits on composition of the dialysis patient population. These data indicate that problems of patient selection have been resolved, and ESRD patients now have equal access to medical care. Nevertheless, there is growing pressure for cost efficiency for the ESRD program in the tightening economic climate. This may lead again to some form of restriction for future access to dialysis therapy.

Adolescent↗

Incidence and prevalence of home dialysis.

The proportion of patients on home hemodialysis in the United States has declined continuously since 1972 despite an increasing total number of patients treated by dialysis. Regional variations and the experience in Europe are described. The reasons for the changing pattern of dialysis in the United States are discussed, together with possible measures which could help to reverse the present trend of increasing use of more expensive center dialysis which has features making rehabilitation more difficult for many patients.

Europe↗