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Biomedical subjects

C R Anderson

Publications and source records attributed to C R Anderson.

88 records · Page 5Linked to original sources
PubMedDate not supplied

Origins of nerve terminals containing nitric oxide synthase in the guinea-pig coeliac ganglion.

Nitric oxide synthase was localised immunohistochemically and by NADPH diaphorase activity in two groups of nerve terminals and in rare cell bodies in the guinea-pig coeliac ganglion. Strongly reactive varicose terminals surrounded a subgroup of principal ganglion cells, most of which were in the medial lobes of the ganglion and most of which were somatostatin immunoreactive. A second set of varicose terminals, which were less intensely reactive, were found throughout the ganglia. Nitric oxide synthase containing nerve cell bodies in the intermediolateral cell columns of the spinal cord were labelled by dye retrogradely transported from the coeliac ganglion. Lesion of nerve connections between abdominal viscera and the coeliac ganglion caused a loss of the strongly reactive fibres, while the widely distributed, less intensely reactive fibres persisted. It is concluded that nitric oxide synthase terminals in the coeliac ganglion come from two sources, sympathetic preganglionic neurons and intestinofugal neurons.

Amidines↗
PubMedDate not supplied

Surgical treatment of adrenocortical tumors: 21 cases (1990-1996).

Twenty-four adrenocortical tumors were surgically removed from 21 dogs. Histopathological examination confirmed 18 carcinomas and six adenomas. Four dogs died in the perioperative period. Fifteen of the 17 dogs that survived the perioperative period had long-term resolution of their clinical signs. Two dogs with incompletely resected tumors were treated with mitotane to control their clinical signs. Overall median Kaplan-Meier life-table survival for dogs with carcinomas was 778 days (range, one to 1,593 days). Median survival for dogs with adenomas was not reached (range, 11 to 730 days). Histopathological diagnosis, histopathological cellular features, age of the dog, and tumor size were not prognostic of outcome.

Adrenal Cortex Neoplasms↗