The use of oxygen tension measurements to indicate local circulatory changes in the gut.
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Biomedical subjects
Publications and source records attributed to C Piasecki.
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Study of intramural vascular pathways to the human gastroduodenal mucosa shows that some persons have patches of mucosa supplied by end arteries. These patches occur only in the ulcer-bearing areas. It is suggested how this may contribute to the initiation of peptic ulceration and explain some of its features.
Arteriolar patterns of the submucous plexus were studied in all areas of the dog's stomach and in the first inch of the duodenum. There appeared to be no poverty of plexus, although in some cases the vessels were somewhat smaller in the pyloric part of the lesser curvature than elsewhere. Mucosal arteries arose from the plexus, and none appeared to have an extramural origin. In man, on the other hand, there is a poverty of the submucous plexus in the 'ulcer region', i.e. in the incisural region of the lesser curvature and in the first inch of the duodenum, associated in some cases with mucosal end arteries of extramural origin. The absence of these features in the dog, which does not suffer from spontaneous chronic ulceration, lends further support to the view that they play a role in the aetiology of the disease in man.
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