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Biomedical subjects

C Peters

Publications and source records attributed to C Peters.

273 records · Page 16Linked to original sources

Exercise, cancer and the immune response of monocytes.

We examined the influence of a regularly moderate endurance training program on qualitative and quantitative alterations of monocytes from 24 breast cancer patients. At the beginning, after 5 weeks and 7 months of bicycle training we analyzed the composition of leucocytes and phagocytotic activity of monocytes using two different methods under resting conditions. At the end of the study the amount of granulocytes was enhanced, but lymphocytes and monocytes were decreased. While the phagocytotic capacity of monocytes increased compared with receptor destroying enzyme-treated sheep red blood cells, phagocytosis against Anti D-loaded human erythrocytes did not change. These different results led us to suggest that physical exercise training increases the number of specific receptors in the surface membrane of monocytes.

Animals↗

Influence of a moderate exercise training on natural killer cytotoxicity and personality traits in cancer patients.

We have investigated the influence of exercise training on natural killer cells and psychological behaviour in cancer patients. 24 women with carcinomas of the breast performed a moderate training program two to three times a week for seven months. At the beginning, after five weeks and at the end of the study we analyzed the amount and the activity of natural killer cells (CD 56) under resting conditions. Personality traits were measured with the FPI-R questionnaire at the same time points. While the amount of natural killer cells did not change, their cytotoxic activity was increased at the end of the study. Furthermore, the discomfort decreased. After 5 weeks satisfaction of life was enhanced and at the end of the investigation we observed a strict connection of this improvement with the frequency of exercise. These results demonstrate a stimulating influence of moderate exercise training on the resting NK-cell activity even in cancer patients.

Adult↗

Affirming the decisions adolescents make about life and death.

Adolescents who are critically, chronically, and terminally ill traditionally have been given little voice in their health care treatment. But over the last three decades attitudes have begun to shift. The legal and medical professions as well as parents and children's advocates have started to recognize that cognitively normal adolescents have decisionmaking capacity and believe these patients ought to have the opportunity to participate in even the toughest of health treatment decisions. Advances directives, if used with sensitivity and care, could prove a valuable means of giving these older pediatric patients a say in their care.

Adolescent↗