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Biomedical subjects

C Papadopoulos

Publications and source records attributed to C Papadopoulos.

7 recordsLinked to original sources
PubMed1992

Intravenous atenolol in elderly patients in the early phase of acute myocardial infarction.

The aim of this study was to assess the hemodynamic response to intravenous atenolol in elderly patients with acute myocardial infarction. We studied 14 elderly men, aged 64-85 years, and 14 younger men, aged 29-48 years, in the early postfibrinolytic phase of acute myocardial infarction. All the patients were in Killip class I. A triple-lumen Swan-Ganz thermodilution catheter was introduced into the right heart chambers. The patients received 5 mg intravenous atenolol over 5 minutes. All hemodynamic parameters were measured before and 10 minutes after atenolol. The hemodynamic characteristics and the location and extent of acute myocardial infarction were the same in both groups before atenolol. The hemodynamic changes after atenolol administration were the same in the two groups, but the stroke volume and cardiac indexes decreased to a greater extent in the elderly (p = .01 and p = .0001, respectively). These results indicate that intravenous atenolol in the early postfibrinolytic phase of acute myocardial infarction is safe in Killip class I elderly patients, although the cardiac and stroke volume indexes decrease, and the increase in the total systemic resistance is more in older than in younger patients.

Adult↗
PubMed1991

Comparison of Q with non-Q myocardial infarction using signal averaged ECG.

Forty consecutive patients (pts) with acute myocardial infarction (MI) who survived to be discharged from the hospital were studied with high gain signal averaged electrocardiography (SAECG). 28% of the pts with non-Q MI had an abnormal SAECG as compared to 15% in the Q MI group. It was also found that SAECG showed a significantly longer filtering QRS duration in the non-Q MI group. The results above were considered as indicative of more delayed activation in pts with non-Q MI providing probably a substrate for more frequent reentrant arrhythmias.

Electrocardiography↗
PubMed1990

Tissue reaction to deep cuff of Tenckhoff's catheter and peritonitis.

To define the type of reaction around the deep cuff of Tenckhoff catheters and possible implications in peritonitis development, a histological evaluation of the tissue reaction around and into the deep cuff was done. Eight catheters, functioning for 2 to 40 months and removed for various reasons were studied. In all cases foreign body granulomata and fibrosis were found, with prominent giant cell formation. An inert birefrigent material, probably dacron particles, was found surrounded by giant cells in fibrotic regions and in some cases appearing as cytoplasmic inclusions. In 6 cases an inflammatory infiltration was observed, while in 4 with relapsing peritonitis, polymorphonuclears and microabscesses were also found. It can be suggested that the tissue reaction to deep cuff predisposes to local infections and might be a factor for relapsing peritonitis.

Adult↗