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Biomedical subjects

C P Freeman

Publications and source records attributed to C P Freeman.

At least 55 records · Page 3Linked to original sources

"Hidden" eating disorders in Scottish psychiatric inpatients.

The authors designed a study to determine the prevalence of "hidden" eating disorders among a large group of hospitalized psychiatric patients. Of 146 patients surveyed, 13.8% currently had eating disorders diagnosed according to DSM-III criteria: 7.3% had bulimia, 3.6% had anorexia nervosa, and 2.9% had an atypical disorder. Eighty percent of the bulimic patients and all of the patients with an atypical disorder had not been so identified by hospital diagnosis. Eating-disordered patients tended to have concurrent diagnoses of affective or personality disorders.

Adolescent↗

Dexamethasone suppression test in depression: association with duration of illness.

Plasma cortisol response to 1 mg dexamethasone suppression test was investigated in 37 patients with primary major depressive illness. Non-suppression of plasma cortisol was found in 14 of 37 (38%) patients. Duration of the index episode of illness was significantly shorter in the non-suppressors (11.1 +/- 9.1 weeks) than in the suppressors (29.7 +/- 25.6 weeks). The two groups were not distinguished by age, sex, polarity or severity of depressive symptoms. Eighty per cent of the non-suppressors (4/5) and 57% of the suppressors (8/14) had severe life events or major difficulties in the 6 months preceding the onset of illness, but this difference failed to reach statistical significance.

Adolescent↗

A study of the incidence of epilepsy following ECT.

In a group of 166 patients who had received electroconvulsive therapy more than one year previously the prevalence of epilepsy did not differ significantly from that found in the community as a whole. The findings suggest that a kindling process is not a clinical hazard following repeated electrically induced seizures.

Adult↗

ECT: II: patients who complain.

Twenty-six subjects who complained of permanent unwanted effects following ECT were compared with two groups of control subjects on a battery of 19 cognitive tests. Many statistically significant differences were found in cognitive functioning, mostly attributable to the level of depression or medication in the complainers. However, after analysis of variance/co-variance some differences still remained, indicating impaired cognitive functioning in the ECT complaining group.

Adult↗

ECT: III: Enduring cognitive deficits?

Cognitive function was compared in carefully matched groups of ECT and non-ECT treated depressives and in matched normal volunteer controls on admission, at 4 months and at 7 months. ECT caused little impairment at 4 months and no impairment at 7 months on a comprehensive cognitive test battery. Severity of depression had a marked effect on cognitive function. Within the ECT group bilateral ECT caused more impairment than unilateral ECT one week after a course but 3 months later the differences had disappeared. They were equally antidepressant.

Adolescent↗

ECT: I. Patients' experiences and attitudes.

One hundred and sixty-six patients who had ECT in either 1971 or 1976 were interviewed. The 1976 samples represented 89 per cent of those available for interview. Their experiences of ECT and their attitudes to it are described. They found ECT a helpful treatment and not particularly frightening, but side-effects, especially memory impairment, were frequent.

Adjustment Disorders↗

The tryptophan requirement of broiler chicks.

The "available" tryptophan requirements of male and female broiler chicks were determined at 7-d intervals from 0 to 56 d, using a diet-dilution technique. Availability of tryptophan in the diets was estimated by growth assay with chicks. 2. The tryptophan requirements were 2.4 (males) and 2.2 g/kg of diet (female) from 0-7 d, and 1.7 g/kg (males and females) from 7-35 and 35-56 d. The absolute requirement of the chick for tryptophan increased with age and was significantly different for male and female birds. 3. A highly significantly predictive equation relating tryptophan requirement to mean body weight and gain was established.

Age Factors↗

How does E.C.T. work?

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Clinical Trials as Topic↗