Biomedical subjects
C P Bournique
Publications and source records attributed to C P Bournique.
[New researches on protein synthesis inhibition under the action of aurintricarboxylic acid during cell cycle : Study on meristematic cells of Allium sativum L].
Aurin tricarboxylic acid, an inhibitor of protein synthesis, prevents cells from entering mitosis in Allium sativum L. root meristems. When the uptake of 3H-leucine comes back up to the control rate after removal of roots from the drug, mitotoic activity is resumed. Furthermore, the percent of labelled cells obtained by continuous labelling with H3-thymidine shows a reversible arrest of cell progress from G1 to S.
[Modality of the antimitotic acitivity of the diamine cis-dichloroplatinum (II) studied on the plant cell].
In the order of decreasing doses, cis-platinum (II) diamine dichloride acting on root meristem of Allium sativum produces first an irreversible metostatic effect quickly followed by lethal effect, then a variable mitodepression accompanied by important chromosomal alterations: numerous disruptions and stickiness. This chromatoclasic effect persists at very low concentrations but stathmodieretic effect is not observed. The chromatoclasic activity of the compound is compared to that of other antitumoral drugs.
[Antimitotic properties of platinum (II) complexes of the type trans PtC12 (olefin) (pyridine). Study by means of the Allium test].
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[Antimitotic activity of 9 methoxy ellipticine lactate. Study on plant cells (Allium test) and on human cells cultivated in vitro].
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[Distribution of chromosomal fragments induced by methoxy-9 ellipticin lactate in human diploid cells cultivated in vitro].
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[The repercussins of spontaneous mitotic abnormalities in Hela cells cultured in vitro on the interpretation of antimitotic effects].
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[Blockage in metaphase by chromatoclasic agents in animal cells cultivated in vitro].
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[Antimitotic activity of a series of ethylene-imine phosphoramide derivatives on HeLa cells].
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[Use of a murine (P-815) mastocyte line in cellular pharmacology. Application to the study of a phosphoramide series].
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[Bismuth in the Allium test: a problem in comparative toxicology].
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