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Biomedical subjects

C Orzincolo

Publications and source records attributed to C Orzincolo.

At least 91 records · Page 5Linked to original sources
PubMed1984

[The elbow exposed to vibrating instruments and idiopathic diffuse skeletal hyperostosis: association or pure coincidence?].

A group of 11 patients with chronic enthesopathy of the elbow caused by vibrating instruments was systematically examined for spinal signs of diffuse idiopathic skeletal hyperostosis (DISH). Nine patients revealed spinal involvement, the two exceptions probably relating to the patients' youth. The findings support the hypothesis that DISH is not a disease but rather a tendency to excessive ossification of ligamentous structures in response to stimuli that generally produce only modest new bone formation. Those suffering from such ossifying diathesis should be directed towards work unlikely to damage the enthesis.

Adult↗
PubMed1984

Periosteal new bone in uraemic osteodystrophy.

Out of 54 patients requiring haemodialysis approximately one quarter were found to have periosteal new bone associated with severe renal osteodystrophy. This feature has been analysed and correlated with biochemical, clinical, and histological parameters. No direct correlation was found with the duration of haemodialysis, but there is a good correlation with histological indices of osteitis fibrosa and serum parathormone levels. Periosteal new bone regressed or totally disappeared in eight patients after parathyroidectomy and renal transplantation. It is suggested that periosteal new bone may be a useful indicator of hyperparathyroidism in this type of patient.

Adult↗
PubMed1984

[Peripheral localizations in diffuse idiopathic skeletal hyperostosis].

The extra-spinal manifestations of diffuse idiopathic skeletal hyperostosis (DISH) are described in 73 consecutive cases, detected during radiographic screening of the thorax for other problems. The characteristic spinal changes (calcification and ossification of the ligaments in the antero-lateral aspects of the vertebral bodies) are present in all individuals. Extra-spinal changes include "whiskering" at the site of the attachment of muscle in the pelvis and long bones, ligament and tendon ossification, periarticular osteophytes, and spurring of the calcaneous and the olecranon. The radiographic patterns in the peripheral skeleton are frequently distinctive and allow the radiologist to suggest the diagnosis, even in the absence of axial radiographs. The diagnosis of DISH is based on preselected radiographic criteria, but the etiology remains elusive.

Adolescent↗
PubMed1984

[Radiographic aspects of the hand in diffuse idiopathic skeletal hyperostosis].

Radiographs of the hand of 53 patients with diffuse idiopathic skeletal hyperostosis (DISH) were compared with 20 acromegalic subjects and 100 matched controls. Bone qualitative changes, characteristic of DISH, include: (1) arrow-heading of the distal phalangeal tufts; (2) enthesopathy of the proximal phalanges; (3) enlarged sesamoid bones; (4) hook-like exostoses at the metacarpophalangeal heads; (5) cortical thickness of diaphyseal tubular bones. Therefore, the hand in this disease appears as a "robust" form, particularly in males, resembling acromegalic pattern, but in this disease, the hand is much more coarse (so called squared hand), especially because of the soft tissue involvement and articular cartilaginous hypertrophy. Only enthesopathy seems to be the most characteristic and peculiar finding of the disease. Quantitative bone change measurements have demonstrated in DISH that metacarpal and Exton Smith indices differ statistically toward the controls. The hand is wider, but in males bone mass may result the same and in female is shortly reduced. Soft tissue alterations, compared with the controls, are not significant. On the contrary, in acromegaly there is a significant statistical difference in all the quantitative measurements of both the skeletal and soft tissue lesions, compared with the controls and patients affected by DISH.

Acromegaly↗
PubMed1983

[Mönckeberg's mediocalcinosis associated with Raynaud's phenomenon].

A case of Mönckeberg's arteriosclerosis associated with Raynaud's phenomenon and diabetes is reported. It is probable that Mönckeberg's arteriosclerosis could provoke a Raynaud's phenomenon when predisposing local conditions, such as microvasculature and/or haemorheological alterations, are present. Finally our findings seem to demonstrate that xeroradiographic investigation is most important for the early diagnosis of the disease.

Aged↗
PubMed1983

[Migration of hepatic macrophages after cyclophosphamide or whole body irradiation].

The liver macrophages behaviour after cyclophosphamide or total-body irradiation (1000 rads - 60Co) has been studied in the mouse previously injected with colloidal carbon. In these conditions an early increase of carbon-laden macrophages in the central zone of the liver lobules has been observed. Carbon-containing mononuclear cells were also observed in the lumina of the hepatic collecting system. Possible implications of these findings are discussed; a migration of macrophages from the liver to elsewhere is suggested.

Animals↗
PubMed1983

[The acromegalic hand. Diagnostic value of various radiographic measurement indices].

The first classic description of so-called "spade hand" in acromegaly dates from 1886 and is reported by Marie [22]. The hand radiograph is easily diagnostic, when gross abnormalities are present. Sometimes, however, it may be difficult to distinguish the appearances of the milder case from the normal, only by X-ray. The aim of this paper is to define the position of several hand measurements (sesamoid index, tufting, joint space thickness, hand length, metacarpal index, soft tissue measurements at index finger) and to compare these indices in relation to the detection of disease in radiological diagnosis. Hand measurements were made in 100 normal controls and in 19 cases of acromegaly, of whom hand radiograph and xerograph were performed and also compared each others.

Acromegaly↗
PubMed1983

[The ribs in beta-thalassemia. Course of the changes in relation to transfusion therapy].

At the present time, the only treatment available to correct the anemia in Cooley's disease is the use of blood transfusions. The patients maintained at a higher baseline level of Hb (Hypertransfusion Regimen = HTR, with Hb levels of 8 divided by 10 g/100 cm3) are in general, in better health and have smaller organs: particularly, the changes in the skull and in other bones become less pronounced and may recede. The authors have reviewed in 77 patients with beta-thalassemia syndromes a spectrum of rib changes, including widening, osteoporosis with or without localized lucencies, "rib-within-a-rib" appearance, subcortical lucency and extramedullary hematopoietic masses. These radiological changes are explained on the basis of the relationship of the proliferating marrow to the medulla, cortex and periosteum. The type of abnormalities depends on the type of transfusion regimen. HTR begun early in life will prevent the development of any abnormal rib changes; on the other hand, in the majority of cases, abnormal findings did not regress with LTR (= Low Transfusion Regimen, with Hb level of 4 divided by 6 g/100 cm3).

Adolescent↗
PubMed1983

[The hand in psoriatic arthropathy. Radiographic and xeroradiographic comparison].

The hands of 45 cases of psoriasis with arthritis and of 100 cases of rheumatoid arthritis without psoriasis were studied by radiographic and xerographic techniques. The characteristic findings of both methods were recorded separately and compared later. In 44% of cases of psoriatic arthritis, radiographic and xerographic changes are indistinguishable from typical rheumatoid arthritis, but with predominant involvement of distal interphalangeal joints, often bilaterally asymmetric. On the contrary, in 31% of cases, erosive polyarthritis associated with proliferation of subperiosteal new bone (enthesopathy) is present, also with characteristic feature of arthritis mutilans. In 25% of cases, psoriasis of the skin and/or nails is associated with clinical manifestations of rheumatoid arthritis, without roentgenographic findings of arthropathy. The xerographs and radiographs of each patient were compared, assessing the degree of subperiosteal erosion, soft tissue swelling, acro-osteolysis, distruction of small joints and osteolysis of the phalanges, bony ankylosis. The soft tissue swelling ("sausage" finger) was more easily demonstrated by xeroradiography than by conventional radiography, because of its wide recording latitude. However, radiograph remains the technique of choice in the assessment of bone changes of the hand, especially at the first stage of arthritides.

Adult↗
PubMed1982

[The hand as an indicator for the diagnostic orientation in various systemic diseases involving the bones].

Radiological aspects of the hand are presented and discussed in connection with some of the more common systemic diseases involving the bones, in which the hand is an ideal diagnostic indicator. Suitable X-ray techniques and xeroradiography are used to identify alterations to the periostium, the bone cortex and marrow and the soft tissues. The different diseases were classified according to the part of the hand involved: a) distal extremities; b) proximal phalanges and metacarpals; c) entire hand; d) wrist area.

Acromegaly↗
PubMed1982

[Skeletal changes in non-Hodgkin lymphoma].

140 patients affected by non-Hodgkin lymphoma (NHL) are performed by the A. Skeletal involvement of metastatic nature is observed in 14 of these (10%). Only the aggressive lymphomas have radiographic bone disseminations. At beginning of disease no patient has interested by bone changes. The most frequent roentgenographic finding observed by the A. include high incidence of osteolityc lesions: in particularly, pattern so called "permeative" is present in 35.6% of cases. Osteosclerotic and mixed manifestations were much less commonly observed (7,2% respectively). Periosteal reactions is not observed in any cases. The value of roentgen skeletal investigation in diagnosis, staging and therapy of NHL is discussed by the A.

Adult↗
PubMed1982

[Skeletal changes in intermediate beta-thalassemia. Clinical and radiological study].

Bone changes of varying degree and distribution were observed by the Authors in 10 carriers of beta-thalassaemia intermedia in skull, ribs, hand, elbow and knee bones. When they are present, skeletal changes are the same of homozygous beta-thalassaemia, but less marked and spread. Instead, symptomatology is more homogeneous, usually characterized by mild anaemia and morphological changes of red cells with haemoglobin values in the 6-11 g/dl range, splenomegaly, jaundice, gallstones, crural ulcers. The clinical state goes through the asymptomatic condition to a more severe condition with typical appearance of Cooley's anaemia.

Adolescent↗
PubMed1982

[Xeroradiography in the study of the "diabetic foot"].

42 patients, 25 males and 17 females, affected by diabetic osteoarthropathy of the foot were examined by the authors by means of xeroradiography. The radiographic findings, already reported in literature, as Charcot's joint and mutilating osteopathy, are better shown by xeroradiography, which allows to appreciate soft tissues, joints and vessels pathologic conditions much better than plain films. Moreover, the edge contrast enhancement and great contrast scale of xeroradiography allow to reproduce in a single image all the structures of the foot, as tarsal metatarsal and falangeal bones (especially in dorso-plantar projection) with optimal reproduction of single foot components and their skeletal structure.

Adolescent↗
PubMed1982

[Xeroradiography in the study of dysmetabolic arthropathies].

70 patients affected by methabolic joint diseases are reviewed. Xeroradiography has been performed in hand, foot and knee for studying soft tissue and bone lesions in 12 subjects affected by chronic gout and 5 by CPPD. Results show that xeroradiography is more effective than X-ray films in outlining soft tissue masses, especially little dystrophic meniscal calcifications, and initial lesions in bone.

Adult↗
PubMed1981

[The evaluation of bone changes in beta-thalassaemias by xeroradiography (author's transl)].

A xeroradiographic investigation of the skull, hand and elbow bones were carried out by the authors in 50 patients with beta-thalassemia major and in 14 with beta-thalassaemia intermedia. The results were extensively compared with x-ray images. The xeroradiographic method, for its edge contrast enhancement effect and great latitude, better documented than x-ray widening of the medullary cavities and cortex thinness in the shaft of long bones. The diploic space of the skull appeared more detailed; the "hair-brush" pattern and outer table were also particularly demonstrated. The use of "positive mode" imaging is the main requirement in the study of skull and extremities. The changes observed with xeroradiography were statistically more characterized than that seen with x-ray, enhancing the evolution of bone involvement due to actual longer survival of these patients.

Adolescent↗
PubMed1980

[Xeroradiographic study of rheumatoid arthritis hand (author's transl)].

The hands of 50 rheumatoid arthritis patients and 32 non-arthritis controls were studied with conventional x-ray and xeroradiography. The xeroradiograph and radiograph of each patient were compared, assessing the degree of subperiosteal erosion, loss of joint space, soft tissue thickening and joint deformity. Each metacarpophalangeal and proximal interphalangeal joint alterations were scored on a 0-3 scale. Comparison between xeroradiographic and radiographic techniques showed that osteoporosis was better documented on conventional x-ray while loss of joint space and synovial thickening on xeroradiographs. In conclusion, conventional x-ray study of rheumatoid arthritis hand is comparable with xeroradiographic one, even if not substitutable.

Adult↗