Search PubMed⌕ Search

Biomedical subjects

C Occella

Publications and source records attributed to C Occella.

At least 19 recordsLinked to original sources
PubMed2002

[Experimental survey of a new topical anti-oxidant based on furfuryl palmitate in the treatment of child's and baby's dermatitis with eczema: results from a multicenter clinical investigation].

In this paper we present the preliminary results of a multi-center clinical investigation carried out on a new topical product (Triderm(R) Lenil+) containing Superoxidodismutase (SOD), 18-beta glycyrrethic acid, Vitamin E, alpha bisabolol and a new patented antioxidant molecule, Furfuryl palmitate. These active agents altogether protect skin from cell damages that promote the inflammatory syndrome; their action is furthermore sustained by agents such as phytosphingosine and phytosterols that act to repair the skin barrier. Furfuryl palmitate is an ester with a strong quenching ability towards the singlet oxygene (1O2) and with a high permeability potential through the biological membranes, thanks to its lipophylic formula. Further than being among the main responsible for skin ageing, the 1O2 is involved in the genesis of many topical pathologies such as allergic and irritant dermatitis, atopic dermatitis, inflammation, psoriasis and sunburns. The product has been extensively tested for its effectiveness and skin tolerability on a selected population of 60 children and babies with age ranging from 2 months to 14 years, suffering mainly with atopic dermatitis and irritant dermatitis. The topical use of the product caused a significant improvement of the inflammatory skin conditions, with evident and fast inflammation and eczema reduction in all the investigated pathologies, as shown in the present study. The product has been formulated in order to avoid any sensitisation risk and did not show any relevant side effect. It is particularly suitable in the treatment of pediatric dermatitis with symptoms like eczema, itching, desquamation and xerosis.

Administration, Topical↗
PubMed1995

Argon laser treatment of cutaneous multiple angiokeratomas.

BACKGROUND: Angiokeratomas are cutaneous vascular lesions with common clinical and histological features: dark red to black papules and ectasia of upper dermis vessels, respectively. Multiple angiokeratomas are difficult to treat because they are often too extensive for surgery and cautery, procedures frequently leading to hemorrhage and scarring. OBJECTIVE: Our report is designed to evaluate the efficacy of argon laser photocoagulation in the treatment of multiple angiokeratomas. METHODS: Two male patients affected by angiokeratoma circumscriptum and angiokeratoma of Fordyce, respectively, were treated using an argon laser under local anesthesia. The laser beam was used as a hemostyptic and to flatten vascular papules by photocoagulation. RESULTS: The cosmetic results of argon laser treatment were good. Posttreatment crusting lasted 2 weeks; 4 months later there was excellent healing without scarring. CONCLUSION: Angiokeratomas respond favorably to argon laser photocoagulation since vascular ectasias are localized in the papillary dermis. Thus, the argon laser offers significant advantages over traditional methods and produces no side effects.

Adult↗
PubMed1989

[Splash rash dermatitis. A case].

The Authors report a case of a folliculitis developed in a woman who used a spa with hydrojet circulation. This dermatitis is due to Pseudomonas aeruginosa, which can colonizes the closed-cycle water systems.

Adult↗
PubMed1989

Falsely elevated urinary level of vanillylmandelic acid induced by griseofulvin.

A 6-year-old girl with mild hepatitis was found to have an elevated urinary level of vanillylmandelic acid (VMA), but no cause for the elevation was found. The patient was receiving griseofulvin for treatment of tinea capitis, and this drug was suspected of causing a falsely elevated urinary VMA level. Four other patients receiving griseofulvin were also found to have elevated urinary VMA levels. In one patient, urinary VMA level determined by an alternate method was normal.

Child↗
PubMed1986

Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases.

Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.

Actins↗