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Biomedical subjects

C O'Dell

Publications and source records attributed to C O'Dell.

27 records · Page 2Linked to original sources
PubMed1991

Teaching employees breast self examination. Factors that may influence practice.

Breast self examination is a widely known technique used for detection of breast lumps. Many women do not practice monthly breast self examination, although it has been proven that with early detection the prognosis of breast cancer can be improved greatly. When tend to be taught, or learn about, breast self examination at an early age. The educational techniques used during the instruction can influence the practice of BSE later on. Health professionals can make a difference in the practice of BSE by communicating the value of this detection technique. BSE is a viable breast cancer detection technique that employees can be taught easily in employee wellness programs by health professionals.

Adult↗
PubMed1989

Typical geriatric accidents and how to prevent them.

Certain accidents tend to be more common in elderly patients. Others are common among the general population and include the elderly in their numbers. These include accidents involving fire, carbon monoxide, food and medications, water, restraints, motor vehicles, and those in the workplace. This article reviews such accidents and discusses basic measures of prevention in which the attentive and comprehensive clinician may play a pivotal role.

Accident Prevention↗
PubMed1988

Atypical presentations of neurological illness in the elderly.

The vicissitudes of aging make diagnosis of neurological disorders in the elderly especially challenging. The manifestations of neurological disease are often varied and confusing, and also may be misleading, since they may indicate a non-neurological condition. The atypical clinical manifestations of several age-prevalent neurological disorders are reviewed, along with appropriate diagnostic strategies.

Aged↗
PubMed1985

Inhibition of peptic activity by sucralfate.

It is known that antacids containing aluminum hydroxide inhibit peptic activity by raising intragastric pH and by adsorbing pepsin. Since sucralfate contains aluminum hydroxide moieties, the possibility that this drug might inhibit peptic activity by these same mechanisms was examined. Sucralfate was incubated at a concentration of 10 mg/ml with samples of human gastric juice having pH values between 1.5 and 4 for 30 minutes at 37 degrees C. The proteolytic activity of the supernatant was then determined at a pH of 2.2 against a bovine hemoglobin substrate. When the initial pH of the gastric juice sample was 1.5, sucralfate was converted to a viscous gel and the pH of the incubation mixture rose to 2.9. However, there was no decrease in the peptic activity of the supernatant. In contrast, when the pH of the gastric juice sample was more than 2, the drug remained in suspension, but there was a graded rise in pH to a maximum of 4.1 and a progressive decrease in peptic activity (determined at a pH of 2.2) to a nadir of 65 percent of the control value. However, because peptic activity declines rapidly at a pH of more than 3, peptic activity at the ambient pH of the samples was reduced to only 25 percent of the control value. The results indicate that at pH values of more than 2, sucralfate inhibits peptic activity by both adsorbing pepsin and buffering hydrogen ions.

Adsorption↗
PubMedDate not supplied

Focus group methodology for patients, parents, and siblings.

This report describes methodology that can be used as a guideline for the planning, conduct, analysis, and interpretation of data from focus groups for parents/caregivers, siblings, and children diagnosed with an illness; the methodology provides tools for the conduct of such groups in the same or similar populations. Separate focus group sessions were conducted for parents/guardians, siblings, and affected children. Methodological enhancements in planning and conducting the focus group sessions include development of a sampling frame to derive a representative group of participants, standardization of procedures through the use of a moderator's training manual tailored to each group, identification of topics to broaden content areas and stimulate discussion, and creation of a comfortable environment in which participants could express issues. Statistical considerations regarding design and conduct of the focus group session, as well as acquisition, analysis, and interpretation of data are presented with regard to validity, reliability, and generalizability of information gathered from focus group interviews. Scripts, topics, and timeframes that were initially devised by content experts were validated further and revised for direct use or adaptation by clinicians in the conduct of focus group sessions for parents/guardians, siblings, and affected children. Application of this methodology is intended to promote generalizability, reliability, and validity of information obtained, and to enable health care practitioners to provide better care to young patients and their families.

Family↗