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Biomedical subjects

C O Solberg

Publications and source records attributed to C O Solberg.

At least 127 records · Page 7Linked to original sources
PubMed1975

[Infections].

Explore the source record for details and available documents.

Cholera↗
PubMed1975

Neutrophil granulocyte function in the early diagnosis of acute myelomonocytic and myeloblastic leukaemia.

The phagocytic and bactericidal activities of neutrophil granulocytes from 5 patients with early acute myelomonocytic or myeloblastic leukaemia and 5 controls have been examined. In each patient the bactericidal activity was lower than in any control and the neutrophil dysfunction was demonstrated before leukaemia could be diagnosed from clinical and haematological findings. During periods of remission, the bactericidal activity was normal. Results of neutrophil granulocyte function studies may be a significant aid in the early diagnosis of acute myelomonocytic and myeloblastic leukaemia.

Adult↗
PubMed1975

Influence of therapeutic concentrations of phenylbutazone on granulocyte function.

The influence of therapeutic concentrations of phenylbutazone on human granulocyte function has been examined using a method which facilitates a precise in vitro evaluation of the phagocytic and bactericidal activities of polymorphonuclear leucocytes. Phenylbutazone caused a marked reduction in intracellular killing of bacteria by the granulocytes. Whether this inhibition of granulocyte function also takes place in vivo resulting in enhanced susceptibility to infection, remains unknown.

Depression, Chemical↗
PubMed1973

Hand carriage of gram-negative bacilli and Staphylococcus aureus.

The influence of hexachlorophane disinfection on the bacterial hand flora of hospital personnel has been examined. Hexachlorophane effectively reduced the total number of bacteria and the staphylococcal carriage. Gram-negative bacilli were isolated from 18.8% of the personnel, and 13% of the carriers continued to carry Gram-negative bacilli for more than six months. The carrier rate was significantly higher among those using hexachlorophane detergents (20.8%) than among those using plain soap (14.1%). Prolonged hand carriage of Gram-negative bacilli was often associated with skin irritation, especially of the nailfolds. Hand carriage may be an important source of Gram-negative infections in hospital, and the increase in these infections may partly be due to extensive use of hexachlorophane preparations.

Bacteria↗