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Biomedical subjects

C Nyssen-Behets

Publications and source records attributed to C Nyssen-Behets.

24 records · Page 2Linked to original sources

Induced acute ischaemia in dog bones: age-related effects.

Acute ischaemia was induced in the lower limb of both growing and adult dogs by injection of the femoral artery with a suspension of carborundum and ground glass in physiological saline. Besides the gangrenous process observed in all the animals, the most striking finding was the quite different reaction between the two groups of dogs. The ischaemic bones of the growing dogs presented a tremendous periosteal woven bone formation and, to a lesser extent, an endosteal one. This new bone apposition was accompanied by compact bone resorption. The osteogenic phenomenon involved in some degree metaphyseal and epiphyseal intertrabecular spaces. This process took place from the 12th day of experiment and was never observed in the adult dogs. It can be interpreted as the result of the transitory periosseous vascular system activity originating from the surrounding soft tissues. Furthermore, the physiological inactivity of the periosteal osteogenic layer in the adult animals is probably responsible for the absence of osteogenic reaction in this experimental group.

Acute Disease↗

[Distribution of haversian remodeling in the human femur by an osteon count. A study of 6 femurs in cadavers].

To estimate the remodelling of diaphyseal compact bone in the femora of five subjects aged between 63 and 83 years, osteons and osteon fragments were counted. The measurements were made from microradiographs of transverse sections at all levels in the diaphysis. The ventral, dorsal, lateral and medial quadrants were considered separately. The mean osteon count was uniform in all quadrants and at all levels in the proximal two-thirds of the diaphysis, but tended to be less in the distal third. In addition, there were nearly always more osteons, complete and fragmented, per square millimetre in the subperitoneal region than in the neighbourhood of the medullary cavity. In older subjects, there does not seem to be a relationship between the remodelling of femoral compact bone and the specific mechanical stresses in each diaphyseal quadrant.

Aged↗

[Anatomical variations at the level of the muscles of the arm].

The muscular anatomical variations of the thoracic member are recorded in a series of 180 subjects. Two muscles are supernumerary: a bilateral accessory coraco-brachialis and a unilateral accessory palmaris longus. Two muscles have additional tendons: the extensor carpi radialis brevis and the extensor digitorum.

Aged↗

Hypermineralized lamellae below the bone surface: a quantitative microradiographic study.

Hypermineralized lamellae similar to interstitial resting lines were identified by microradiography beneath haversian, endocortical, and trabecular resting surfaces in 42 subjects aged 18-96 years. In cross-sectioned osteons, this hypermineralized lamella appeared as a circle showing the same high microdensity as the inner margin of the haversian canal. Bone tissue separating this circle and the margin was more mineralized than the peripheral lamellae of the osteon. In the tibia, 13.7 +/- 0.9% (Mean +/- SE) of Haversian canals exhibited a hypermineralized circle, localized at a distance of 20 +/- 0.4 microns from the canal wall. The scalloped haversian canals, different from osteoclastic resorption cavities, represented 9.9 +/- 0.7% of the haversian canals. There was a significant correlation between both types of haversian canals. Therefore, hypermineralized lamellae can appear at the end of bone apposition, whatever the bone surface. Their high mineral content may secondarily lead to an increased brittleness of the most superficial lamellae and even to their disaggregation.

Adolescent↗

Skeletal growth and chondroid tissue.

Membranous and endochondral ossification processes are insufficient to describe all the aspects observed in the growing skeleton. The presence of chondroid tissue that we have identified by means of all modern histological techniques, including those able to detect the different types of collagen, has also to be explained. Present in the mandibular symphysis of either the human or cat fetuses, chondroid tissue has also been observed in the other parts of the mandible, in the sutural areas of the skull and in all the bones of both axial and appendicular skeleton. The differentiation of the mesenchyme into chondroid tissue could probably be related with mechanical forces exerted simultaneously in opposite directions or with a transient ischemia.

Animals↗