Search PubMed⌕ Search

Biomedical subjects

C Nowak

Publications and source records attributed to C Nowak.

At least 19 recordsLinked to original sources
PubMed1990

Induction of sister chromatid exchanges with hypotonic treatment.

Hypotonic NaCl solutions and diluted culture medium were tested for induction of sister chromatid exchanges (SCEs) and chromosomal aberrations (CA). Hypotonic treatment conditions were found to induce high frequencies of CA and SCEs. However, an increase in SCEs was observed only in cells that also had CA. Possible lesions and mechanisms leading to SCEs and CA are discussed.

Animals↗
PubMed1979

[Studies on biological characterization of mammary tumours of the Sprague-Dawley-rat in the syngeneic tumour-host system. III. Metastatic experiments with primary tumours, transplantation passages and metastatic cells (author's transl)].

The metastatic spread following intravenous application of cells from primary and transplanted mammary carcinomas is described. When using cells from primary tumours the incidence rate was between 0 and 17%, but was much higher in the case of advanced tumours (transplantation passages and metastases).

Animals↗
PubMed1979

[Antineoplastic activity of the anthracycline antibiotic violamycin BI in mice and rats using experimental metastases models (author's transl)].

The report describes the antineoplastic activity of violamycin BI on three rodent tumour systems. The test systems are two syngeneic mouse tumours: a benzo(a)pyrene induced sarcoma and a spontaneously originated mammary carcinoma of the inbred strain XVII/Berlin. Both tumours grow in ascitic form and were weekly passaged by i.p. administrations. A third system is a dimethylhydrazine induced rectum carcinoma of the Wistar rat. This rat tumour represents a slowly growing system transplanted by s.c. administrations of tumour fragments. The principle of the screening consists of the evaluation of metastatic parameters, e.g. weight, number and growth rate of metastases, experimentally induced by i.v. administrations of tumour cell suspensions. Under the given experimental conditions violamycin BI represents an antineoplastic antibiotikum with a good effectivity which is superior to the effectivity of the reference antibiotic daunorubicin.

Aminoglycosides↗
PubMed1978

[Plagiocephaly].

Explore the source record for details and available documents.

Adult↗