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Biomedical subjects

C Nava

Publications and source records attributed to C Nava.

At least 73 records · Page 4Linked to original sources
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[Allergic disease caused by squaric acid dibutyl ester: description of 2 cases in a work environment].

The paper describes an episode of contact dermatitis in 4 pharmaceutical industry workers. Symptoms regressed after cessation of exposure. Each worker underwent clinical investigations with specific patch tests for the products handled. In 2 subjects there were positive skin reactions to squaric acid dibutyl-ester, a substance with powerful allergenic action and consequently rarely used on the market. Following elimination of the compound from the production cycle, no further cases of dermal symptoms were reported among the operators.

Adolescent↗
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[Haptens].

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Antibodies, Monoclonal↗
PubMedDate not supplied

[Contact dermatitis of the hands in housewives: preliminary data of a multicenter study].

The preliminary results of a survey carried out by the Institutes of Dermatology of Bari and Florence Universities and by the Clinica del Lavoro of Milan University are analyzed. The survey, whose aim is to identify the causes of contact dermatitis on housewives' hands and whose conclusions are forecasted for June 1990, will examine 1,650 female people, 1,050 of which are ill and 600 are case-controls. The results of the first 617 cases (514 ill and 103 case-controls) are reported. The anamnesis has shown that the hands (in 488 cases) are the most affected part of the body, that the most frequent symptoms are itch and burning sensation (in 410 cases), and that cosmetics, followed by detergents and softeners, are considered by the patients among the products more responsible for these symptoms. The allergic tests, even if with a different percentage of incidence, have shown metals (above all nickel), rubber additives and resins as the main aptens. Another survey, also in progress, concerning the search of metals in detergents and in washing waters for pollution caused by abrasives, pots, Inox sinks, pipes and tabs of the water system, is reported.

Dermatitis, Contact↗
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[Dermatopathies in the domestic worker: the Lombard experience].

In order to identify the etiopathogenesis of cutaneous diseases in housewives, a questionnaire was made, and the gathered data are here described. 1,824 people have answered this questionnaire: 1,007 have reported lesions with a suspicious immunological pathogenesis. The commercial products which were reported as a cause of the dermatitis have been 834. In a group of 142 housewives (86 with allergic contact dermatitis and 56 with irritative contact dermatitis), the allergic sensitizations to the chemicals in the detergents were tested. 21% of the cases had positive cutaneous reactions for nickel salts and 8.4% for chromium salts. The analysis in atomic absorption method of these metals in 34 commercial products has shown their presence in almost all the samples. Hypothesis are formulated to find the source of these polluting substances. The aims and the methods of a investigation carried out on 1.800 housewives, who are going to be controlled in order to estimate the prevalence, the clinical kinds and the etiopathogenesis of dermatitis related to house work, are described. The study will be carried out at the Occupational Health Institute "Clinica del Lavoro L. Devoto" of Milan and at the Dermatological Departments of the Universities of Bari and Florence.

Dermatitis, Occupational↗