Search PubMed⌕ Search

Biomedical subjects

C Morris

Publications and source records attributed to C Morris.

At least 235 records · Page 13Linked to original sources

Assessment of nutritional correlates of blood pressure.

Nutritional factors are thought to contribute to the development of hypertension in susceptible humans. This review categorizes the types of nutrition-related data currently available on the relation between diet and blood pressure and provides guidelines for interpreting and using these data. The nutrition data base and the net effect of specific nutrients on blood pressure are discussed, and examples from the Health and Nutrition Examination Survey are given to compare demographic characteristics of various nutrients with demographic characteristics of hypertension in our society. Criteria for evaluating the strength and relevance of a specific nutrient's influence on blood pressure are presented. A comprehensive, continued assessment of all studies of diet and blood pressure control should assure better understanding of the pathogenesis and treatment of human hypertension.

Adult↗

Voltage oscillations in the barnacle giant muscle fiber.

Barnacle muscle fibers subjected to constant current stimulation produce a variety of types of oscillatory behavior when the internal medium contains the Ca++ chelator EGTA. Oscillations are abolished if Ca++ is removed from the external medium, or if the K+ conductance is blocked. Available voltage-clamp data indicate that the cell's active conductance systems are exceptionally simple. Given the complexity of barnacle fiber voltage behavior, this seems paradoxical. This paper presents an analysis of the possible modes of behavior available to a system of two noninactivating conductance mechanisms, and indicates a good correspondence to the types of behavior exhibited by barnacle fiber. The differential equations of a simple equivalent circuit for the fiber are dealt with by means of some of the mathematical techniques of nonlinear mechanics. General features of the system are (a) a propensity to produce damped or sustained oscillations over a rather broad parameter range, and (b) considerable latitude in the shape of the oscillatory potentials. It is concluded that for cells subject to changeable parameters (either from cell to cell or with time during cellular activity), a system dominated by two noninactivating conductances can exhibit varied oscillatory and bistable behavior.

Action Potentials↗

Hospitals: problems of creating a sense of security.

Next week British and American experts will meet in a hospital security management seminar to be held at Charing Cross Hospital, London, under the auspices of the International Association for Hospital Security. In this article, Charles Morris, district security officer, Central Derbyshire Health District, looks at hospital security in the context of the British NHS and its current financial problems.

Accident Prevention↗

Defective devices--who's liable?

Biomedical engineering know-how and ingenuity have created numerous new implanted and externally used products that have considerably advanced patient care. However, some devices have developed unanticipated problems, leading to complex medicolegal situations.

Equipment and Supplies, Hospital↗

Hypermethioninemia in an infant.

We discuss an infant with hepatitis and hypermethioninemia. An inborn error of metabolism, such as methionine adenosyltransferase deficiency or hereditary tyrosinemia, was originally thought to be the basis for these abnormalities. The infant's subsequent clinical course, however, was incompatible with such a diagnosis; the hypermethioninemia was instead due to the trilogy of prematurity, hepatitis, and a high-protein, high-methionine diet.

Amino Acid Metabolism, Inborn Errors↗

When is a hospital liable for its physicians?

As a general rule of law, the private, charitable hospital bears no liability to the patient who is injured in the hospital by a physician while being treated as that physician's private patient. However, there are exceptions to this rule. Ever since the Darling decision, the courts have been imposing more and more responsibility upon hospital administration, and ultimately the board of trustees, for acts occurring within the hospital's walls.

Governing Board↗

The effects of fast neutrons and X rays on the subependymal layer of the rat brain.

Some effects of irradiation of rat brain with single doses of X rays or fast neutrons have been measured. This was done by estimating the total number of cells in the subependymal layer at various times after irradiation. The gross response to X rays and neutrons was somewhat different, and the results suggest that the two histologically distinguishable cell types in the subependymal layer have different values of RBE.

Animals↗