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Biomedical subjects

C Morocutti

Publications and source records attributed to C Morocutti.

At least 55 records · Page 3Linked to original sources
PubMed1984

Effects of distraction on the contingent negative variation in presenile dementia and normal subjects.

The authors recorded contingent negative variation (CNV) in a group of subjects affected by presenile dementia, at the onset of the symptoms, with a slight degree of intellectual deterioration. Recordings were carried out in rest basal conditions and upon administration of an insignificant distracting stimulus. Results were compared with data obtained in a group of normal subjects of the same age under the same experimental conditions. In the patients a marked decrease of the wave was observed upon the administration of a distracting stimulus.

Attention↗
PubMed1984

Electrophysiological (CNV) analysis of personality traits under stress.

Contingent negative variation (CNV) recordings were performed in 55 healthy volunteers under stress condition (experimentally induced pain). A total of 20 subjects were included in the control group (no painful administration). In the tested group (n = 35) the painful stimulus was delivered before S1, between S2 and S1, and before S2. In the control group there were no changes in CNV parameters. Conversely, among the tested group a positive correlation was found between CNV values (whenever the painful stimulus was administered before S1 as well as before S2) and the highest scores in the State Trait Anxiety Inventory X 2 test. In addition, all individuals displayed the appearance of a positive deflection with a latency of about 300 ms from S2 when the experimental stress was given before S2. Furthermore, the postimperative negative variation (PINV) appeared in 13 out of 35 subjects. There was a strong correlation between the latter electrophysiological phenomenon and the Nowlis test. Our findings suggest that CNV study is useful for the investigation of personality traits in human beings under stress conditions.

Adult↗
PubMed1984

Contingent negative variation and schizophrenia: a long-term follow-up study.

The CNVs of three disorganized schizophrenics and three paranoid schizophrenics were studied longitudinally over a 5-year period. The CNV of the disorganized-type schizophrenics reached its maximum decrease within 3 years of disease onset. A more gradual and less accentuated decrease was noted in the paranoid group within a span of 5 years.

Adolescent↗
PubMed1983

Contingent negative variation and phobic disorders.

The authors studied the modifications in contingent negative variation (CNV) in a group of rupophobic subjects. A slide-projected phobogenic or a neutral stimulus was administered 5 s prior to the warning stimulus (S1). A marked reduction in CNV amplitude and the appearance of post-imperative negative variation were observed when the phobogenic stimulus was applied. No significant variations were noted after administration of a neutral stimulus. The results are discussed on the basis of psychological and neurophysiological findings concerning the relationship between attention, arousal and CNV.

Adult↗
PubMed1983

Subjective posttraumatic syndrome. A comparison of visual and brain stem auditory evoked responses.

Evoked responses testing including pattern visual evoked potentials (VEPs) and brain stem auditory evoked potentials (BAEPs) were performed in 57 subjects suffering from subjective posttraumatic syndrome (SPTS). 36 of them had loss of consciousness after head injury. Abnormalities were found in 12 subjects out of 57 (21%). In addition, the pathological findings by percentage were: 25% in subjects who had loss of consciousness after head injury (9 cases out of 36) and 14% in subjects without loss of consciousness (3 cases out of 21). Evoked response alterations were more frequent in subjects with frontal and/or occipital trauma; BAEP abnormalities were found to be more frequent than VEPs. Our findings suggest that evoked responses testing could be a useful noninvasive technique to evidence an organic dysfunction of CNS in some subjects with SPTS.

Adult↗
PubMed1983

Brain slow potentials (CNV), prolactin, and schizophrenia.

This is a study of possible CNV correlations to schizophrenia. Three groups of schizophrenic patients were examined: 14 patients with an initial acute psychotic illness, before and after neuroleptic therapy; 9 subjects with chronic schizophrenia, who did not require continuous neuroleptic therapy; 18 patients with chronic schizophrenia under almost continuous neuroleptic therapy for many years. The results were compared with CNV parameters of a control group. On the basis of the results obtained, the authors advance the view that the different modes of manifestation of cerebral bioelectric reactivity (CNV) are independent of treatment and are related to the different stages of the evolution of the disorder.

Adult↗
PubMed1982

Electrophysiological measures (CNV--EEG) and nitrous oxide at low doses in man.

Nitrous oxide (N2O) is a widely used inhalational anesthetic gas, but its exact mode of action and its distribution in the CNS are not yet well known. The aim of this research was to study the effects of N2O at low doses (10 percent) in the CNS of humans. Five healthy volunteers were tested. Contingent Negative Variation (CNV), Reaction time (RT) and quantified EEG recordings were taken while subjects were breathing air and then N2O. A significant reduction of the post-imperative positive CNV components during N2O inhalation was observed; no changes in EEG power spectrum and RT values were seen. These results could be consistent with an early N2O interference with processes underlying CNV resolution, while vigilance and attention were still maintained.

Adult↗
PubMed1980

Brain slow potentials and hypnosis.

Contingent negative variation behavior was studied in 12 voluntary normal subjects in basal conditions and in the hypnotic trance state under different emotional suggestions. A CNV voltage decrease and the appearance of a PINV were observed in the hypnotic state. Furthermore 12 nonhypnotizable control subjects were tested under the same experimental conditions and no CNV modification was found.

Adult↗
PubMed1979

A longitudinal CNV study in a group of five bipolar cyclothymic patients.

The authors carried out a longitudinal study in five subjects with bipolar cyclothymic psychosis, recording contingent negative variations in the same patients in the different phases of illness and under normal clinical conditions. An average voltage decrease was found in the depressive phases and a more conspicuous decrease in the manic phases. Furthermore, an evident postimperative negative variation was present in four subjects during the manic phase. The authors set forth tentative psychological and neurophysiological interpretation of their results.

Adult↗