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Biomedical subjects

C Moll

Publications and source records attributed to C Moll.

43 records · Page 3Linked to original sources
PubMed1982

Hereditary neuropathy with liability to pressure palsies. Report of two families and review of the literature.

Clinical, neurophysiological and pathological investigations were carried out in 11 affected members of 2 families with hereditary neuropathy with liability to pressure palsies (HNPP). The observations were related to findings in 261 cases of 47 families published in the literature. It was concluded that HNPP is a nosological entity characterized by the following diagnostic criteria: (1) an autosomal dominant inheritance; (2) the clinical presentation of a recurrent mononeuropathy simplex or multiplex, frequently related to an inadequate trauma to peripheral nerves; (3) a significant slowing of motor and sensory conduction velocity in clinically affected, but also in clinically unaffected nerves; (4) characteristic morphological findings in sural nerve biopsy featuring "tomaculous" swellings of myelin sheaths, transnodal myelination and segmental demyelination. The pathogenesis of HNPP is not clear. Hypothetical explanations of the pathogenesis of HNPP are discussed.

Adult↗
PubMed1978

[Histomechanical studies on test specimens from hyaline cartilage under compressive loading with regard to rheology (author's transl)].

Modified rheological methods from high polymer physics (biorheology, historheology) have been applied to the testing of hyaline cartilage histomechanics. The following histomechanical properties of cartilage are discussed: transient behaviour, the influence of the mechanical history on the subsequent force-deformation processes, viscoelastic equilibrium status (histomechanical steady state), and relaxation phenomena in the pressure and tension range under alternating pressure-tension loading. Pressure force-time input and output curves in a closed loop system and the amplitude-increasing phenomenon under uniform sinus deformations with increasing superimposed linear deformation input were also demonstrated. The results are discussed from the point of view of functional anatomy.

Animals↗
PubMed1977

[Tissue mechanical behavior of tendinous fibers under statistical and dynamic requirements].

With a device for dynamical processes tension tests were performed on bundles of collagen fibres of human and bovin origin. Part of the studies were performed under statical condition with an universal materials testing machine, equipped with a closed loop feed back control system. If the force is to be kept constant subsequently to a strain process on a collagen fiber bundle (isotonic condition), the fiber length must increase (creep phenomenon, retardation). The force decreases under constant length after a preceding strain process (relaxation). In analogy to the statical relaxation, statical isorheological line, and statical force recovery curve the dynamical (cyclic) relaxation, dynamical (cyclic) isorheological curve, and dynamical (cyclic) force recovery curve are described. The mechanical-rheological properties collagen fiber bundles are discussed in relation to functional anatomy.

Biomechanical Phenomena↗
PubMedDate not supplied

Tuberculoma mimicking meningioma of the falx cerebri. PCR diagnosis of mycobacterial DNA from formalin-fixed tissue.

We describe a 47-year-old patient with intracerebral tuberculoma of the falx cerebri and fronto-parietal cerebral cortex. The patient presented after a single episode of epileptic seizures. Computed tomography and MRI scans were suggestive of meningioma. At surgery a granulomatous tumor was removed that adhered to the cerebral cortex. The diagnosis of tuberculoma was verified by histology and growth in culture of mycobacterium tuberculosis. The patient recovered after surgery and chemotherapy. Three years later we confirmed the diagnosis using polymerase chain reaction for mycobacterial DNA sequences on the formalin-fixed, paraffin-embedded tissue.

Brain↗