New directions in nursing ethics.
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Biomedical subjects
Publications and source records attributed to C Mitchell.
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The incidences of selected events were analyzed following insertion of the PROGESTASERT intrauterine progesterone contraceptive system (IPCS) and following its reinsertion after one year of use. Reinsertion did not interrupt the stabilizing or declining trends in incidences of P.I.D., removals for bleeding/pain, removals for other medical reasons, unplanned pregnancies, moderate/severe menstrual cramps and bleeding, and premenstrual/intermenstrual cramps. Comparison of the incidence of P.I.D. in the U.S. population with postinsertion incidence of P.I.D. in IPCS users indicates that the IPCS does not increase the likelihood that a woman will have P.I.D. over the likelihood that she would have it without use of the IPCS. The incidences of expulsions and intermenstrual spotting and bleeding rose temporarily after reinsertion to about half their previous peaks and then diminished markedly within two months, reverting to the levels and favorable patterns of change established during the first year.
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A tone-on-tone masking paradigm was used to determine tuning curves of cochlear and brainstem responses in the guinea pig. The tuning curves are considered to be a measure of the frequency specificity of these potentials. Calculated Q10 values are used in an indicator of the sharpness of tuning of these potentials. The tuning curves of cochlear and brainstem responses were found to be similar with both showing considerable frequency specificity.
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The relationship between reflection-impulsivity, hypothese generation and testing, and evaluation of the quality of one's own solutions was explored in the framework of Kagan's theory. The Matching Familiar Figures test (MFF) and a pattern-matching task were administered to 94 children from 8-0 to 11-11 years. Multiple regression analyses and analyses of variance showed that children who were inaccurate on the MFF were more likely to offer a solution on the pattern-matching task before they had sufficient information to guarantee a correct solution and to make errors despite sufficient information to have avoided those errors. Thus reflection-impulsivity as measured by the MFF were related to 2 other measures of the evaluation process on another visual match-to-sample task. Only 1 of 3 hypothesis-testing variables was significantly related to MFF performance, and that relationship was rather small.
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The effect of acoustic overload on the N1 potential at different frequences was determined. The conditions of overstimulation were such as to produce temporary effects. The results of the study were: (1) the N1 potential was substantially depressed by acoustic overloads that did not alter the alternating current (AC) cochlear potential; (2) the maximum N1 depression was at one-half octave above the overstimulation frequency; (3) there was no N1 depression at frequencies below the frequency of overstimulation; and (4) the N1 depression recovered within 24 hours.
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Nineteen normal and 22 hearing impaired subjects were used in this study. Thresholds were determined by the following methods: 1. behavioral continuous tone, 2. behavioral tone burst, and 3. the brain stem electric response (BER) with tone bursts. A comparison of the BER thresholds with the behavioral thresholds are made for each subject. The difference between these three measures of threshold suggests that audiograms can be derived from the brain stem response threshold. The derived audiogram compares favorably with conventional audiograms. However, it must be remembered that the brain stem response is not hearing.
In July 1975 the Food and Drug Administration proposed a patient information package insert for all women considering use of an intrauterine device. In the same year we also prepared a brochure to be given to women considering use of a specific intrauterine contraceptive, the PROGESTASERT system. To compare these information sources for the patient, we surveyed by mail 253 women who are or had been PROGESTASERT system users. Each woman received either the FDA or our own prepared version. Comprehension of the two inserts was generally comparable, but readers of our insert found its informational content more complete. The survey findings affirmed the desirability of providing the patient with an educational brochure to be read prior to IUD insertion.
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