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Biomedical subjects

C Miani

Publications and source records attributed to C Miani.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[Pulp and dentin responses to topical dexamethasone application].

The Authors have proposed to develop this research employing a preparation containing exclusively a cortisonic, the desametazone, in order to evaluate the alterations of the dentinogenesis to be attributed to such component. 32 cavities have been carefully drilled in dogs' cuspids. The 16 experimental cavities were dressed with desametazone, asbestos and amalgam in successive strata while in the 16 control cavities only asbestos and amalgam were used. Stainless steel bands were cemented on the processed teeth. The animals received 9 I.V. injections of tetracycline (10 mg per kg) each at 7 days interval. In the observation of the tetracycline markings under the experimental cavities (with desametazone) alterations of the dentinogenesis were not observed. Consequently, it seems that the action of desametazone is not to be considered harmful for the pulp tissue under the freshly cut dentine, as far as duration of the experiment is concerned.

Administration, Topical↗
PubMedDate not supplied

[Aspects of auditory short-term memory according to a multimodal sequence paradigm].

Capacity and temporal characteristics of auditory short-term memory have been investigated through a simple multi-tonal sequence paradigm in five normally hearing subjects. They were required to judge whether the tonal sequence contained or not a tone probe following the sequence. Performance was evaluated relative to the sequence length (2, 4, 6 stimuli) and sequence-probe interval (1, 3, 6 s.). The subjects' performance has been proven to be mainly dependent on the number of the sequence components (90% of the explained variance), while sequence-probe interval represents a factor of minor weight. Furthermore, a strong recency effect has been shown for the last sequence component, extending to the preceding components in dependence of the sequence-probe interval. Contrasting to studies on the verbal short-term memory, a primary effect has been not demonstrated. As these results reflect the typical effects of auditory short-term memory, it is likely that memory tests based on simple tonal sequences may be suitable for clinical use.

Acoustic Stimulation↗
PubMedDate not supplied

[The quantitative effects of competition on verbal intelligibility in the elderly].

The Speech Reception Threshold (SRT) was adaptively measured using sentences in two groups of subjects: young, normal-hearing subjects and elderly hearing-impaired subjects with high frequency loss. SRT was recorded in quiet and in noisy conditions with competition consisting in "speech noise" and continuous discourse delivered at intensities between 11.4 and 98.6 dBA SPL. A significant difference was found between the groups in that elderly subjects had higher SRTs in noise than the young counterparts expressed as signal to noise (s/n) ratio. Moreover, at noise intensities typical of everyday life, the SRTs of the elderly is 6 and 11.4 dBs/n higher than normal-hearing subjects, with speech noise and discourse respectively as competition. Communicative strategies that enhance s/n ratio should be considered in order to overcome the heavy effects of hearing loss in the elderly.

Adult↗