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Biomedical subjects

C McNeil

Publications and source records attributed to C McNeil.

At least 73 records · Page 4Linked to original sources

The effects of cadmium in vitro on adenosine triphosphatase system and protection by thiol reagents in rat brain microsomes.

Cadmium (Cd) inhibited the activities of Na(+)-K+ ATPase (IC50 = 5.0 x 10(-5) M), K(+)-p-nitrophenyl phosphatase (PNPPase) (IC50 = 4.0 x 10(-5) M) and 3H-ouabain binding (IC50 = 7.5 x 10(-5) M) in rat brain microsomes. Monothiols (cysteine but not glutathione and D-penicillamine) and dithiols (dimercaprol, dimercaptosuccinic acid and dithiothreitol) offered varied levels of protection against Cd-inhibition of Na(+)-K+ ATPase. Protection of Na(+)-K+ ATPase by these sulfhydryl (SH) agents was higher at 7.5 as compared to 8.5 pH. The present data suggest that Cd-inhibited Na(+)-K+ ATPase, by interfering with phosphorylation of enzyme molecule and dephosphorylation of the enzyme-phosphoryl complex and exerts a similar effect to that of SH-blocking agents.

Animals↗

From migration to palliation: uncharted waters.

Attention to the unique health care needs of people who have immigrated to Canada should not wait until they are dying. The culture of the past and the reasons for migration are blended into their understanding of health care values and affect their response to interventions. Health professionals should understand that the family and the cultural community play a special role in the integration and acceptance of Canadian methods of care. Palliative home care nurses are participant-observers of the family ties to the past. They can share these observations with other health care workers.

Canada↗

Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.

The growth in the dental literature continues to escalate, as evidenced by the publication of at least 326 new books in 1988 and 1989 and more than 20 new journals in 1989. There still appears to be undue emphasis on quantity instead of quality of research. This proliferation in the literature poses ever increasing difficulties to this Committee in filtering out the articles that are of particular interest to the members of the Academy and identifying those that are most likely to have a major impact on dental practice and service. The subjects covered include periodontics, caries and preventive dentistry, craniomandibular disorders, occlusion, pulp biology, ceramics, and restorative dental materials.

Dental Caries↗

Culture: the impact on health care.

Cultural and ethnic issues are not examined in traditional health care professional education. Our experience in providing care for terminally ill cancer patients in their homes in a multicultural metropolitan area has demonstrated repeatedly the importance of these issues. They can help us to understand how illness is perceived, who provides care, how it is provided, and how health care professionals are accepted. In order to sensitize health professionals to important health/cultural values, a multicultural resource center in our city invites lecturers to speak on health related issues, ranging from nutritional attitudes to religious taboos. Workshops geared toward specific disciplines are available at another resource center. Inservice education on palliative care, offered one hour a week, is one method of highlighting cultural issues for the staff. General nursing rounds, presented once a month for the hospital, is another, as is the hospital nursing journal, which has a column for multicultural contributions. A complete cultural assessment is anthropologically oriented, but a shortened version, dealing with the family hierarchy of power, a cultural/medical assessment, and an awareness of general behavioural differences can help bridge the cultural gap. This paper will present a practical model of cultural assessment that can be used by health professionals. It will suggest simple interventions that can be incorporated in a health care plan.

Curriculum↗

Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.

Dental research continued to grow during 1988. Unfortunately the quality does not always parallel the quantity of publications. This report obviously does not encompass all of the literature but focuses on studies that are related to trends and to matters that are considered controversial. Likewise the particular interests of the members of the American Academy of Restorative Dentistry were taken into consideration. The subjects covered include periodontics, preventive dentistry, bulp biology, craniomandibular disorders, ceramics, color in restorative dentistry, and dental materials.

Dental Materials↗