A comparison of the effects of a thromboxane antagonist and cyclo-oxygenase inhibitor on platelet accumulation in arterial grafts.
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Aorta↗
Biomedical subjects
C McCollum
Publications and source records attributed to C McCollum.
Simultaneous kidney and pancreas transplantation in man.
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Adolescent↗
Community leg ulcer clinics: cost-effectiveness.
This study investigates the cost-effectiveness and efficacy of a new service provided by community leg ulcer clinics, and compares it with treatment in existing hospital-based venous ulcer care clinics. Data were provided prospectively from district nurses and retrospectively from patients. Success in treatment was assessed as a percentage of ulcers completely healed after 12 weeks of treatment, analysed by the up-table method. Treatment success of 22% at 12 weeks using existing methods compared with 80% in community clinics. Costs were estimated to be 433,600 pounds and 169,000 pounds respectively. These findings indicate that community leg ulcer clinics were more effective and less expensive than the previous system of care.
Aged↗
Leg ulcer care: an audit of cost-effectiveness.
Our objective was to establish an audit mechanism to determine the cost and effectiveness of leg ulcer care across two Health Authorities. Following identification of all patients with active ulcers over a two-month period, leg ulcer treatment, costs and outcome were prospectively audited over three months. We found that leg ulcer care is currently expensive and appears to be largely ineffective, especially when compared to the community clinic approach.
Cost-Benefit Analysis↗
Rapid and efficient oligonucleotide synthesis with low reagent consumption via a new synthesis column design: preparation of fluorescent dye labelled primers for application in PCR.
A low dead-volume, 40 nmole scale column was designed for automated, solid-support oligonucleotide synthesis. The LV40 columns are filled with 1000A, high-cross link polystyrene beads at the 40 nmole scale. Reducing the unoccupied volume and optimizing the column dimensions allows efficient and fast synthesis on existing commercial synthesizers with low reagent consumption. Three spectrally distinct fluorescent dyes were applied as phosphoramidites in the synthesis of PCR primers. Fluorescent labelled PCR products of the Mfd11 microsatellite locus were analyzed.
Chromatography, High Pressure Liquid↗