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Biomedical subjects

C Mascrès

Publications and source records attributed to C Mascrès.

At least 19 recordsLinked to original sources
PubMed1997

[Ectodermal dysplasia: multiple manifestations of a hereditary disease].

Ectodermal dysplasia is a hereditary disease that can manifest itself in many ways. Four cases, including two cases involving heterozygote twins, are presented. The clinical signs of the disease, as observed are compared to the knowledge offered in the classic and modern literature. Special attention is given to the intraoral manifestations of the disease, and to the solutions that a multidisciplinary dental team could consider to improve the masticatory function and the facial esthetics of patients affected by this disease.

Anodontia↗
PubMed1995

[Herpesvirus infection: from the primary oral lesion to recurrent herpes].

This paper presents an overview of the clinical conditions associated with a herpetic lesion at the time of the primary infection, as a true primary infection or a first herpetic accident, or during recurrences. The virus responsible, its anatomy and its functioning are detailed. The etiology and transmission of herpetic viral infection, its evolution and complications, as well as diagnostic aids are also discussed. To complete the discussion of this chronic disease which can cause acute annoyances treatment, particularly for children is reviewed, and suggestions are made to prevent it.

Acyclovir↗
PubMed1993

A comparison of the effects of two hydroxyapatites and a methacrylate resin on bone formation in the rat ilium.

The bone response to two hydroxyapatite (HA) products (Osteogen and Alveograf) and a porous methacrylate resin material (HTR) in rats was compared. Fifty rats had four holes drilled in each iliac crest. The three alloplasts were placed in separate cavities and the fourth cavity was left empty as an absolute control. The survival times varied. The results were evaluated by subjective and histomorphometric analysis. Data were analyzed with ANOVA. There was a statistical difference in bone apposition between HTR and the HA products. The HTR was less osteoconductive, while HA consistently showed dense bone formation. The HA products are generally associated with greater bone formation, suggesting that HA is a better material for bone replacement than HTR.

Analysis of Variance↗
PubMed1992

Reaction of the dental pulp to hydroxyapatite.

The purpose of this study was to evaluate the action of hydroxyapatite (HA) (Osteogen HA Resorb, GBD Marketing Group Inc., Valley Stream, N.Y.) on the dental pulp of rats. Four upper molar pulps in 45 rats were exposed and capped with synthetic HA (Osteogen) with a stereoscopic microscope. Pulps capped with calcium hydroxide (Dycal, L.D. Caulk Co., Milford, Del.) served as controls. The cavities were filled with amalgam, and the molars on each side of the maxilla were protected by the placement of a pedodontic steel crown. Pulp inflammation and dentin repair were compared by histologic observations and computer image analysis after 7, 14, and 28 days. After 7 days a partial acute pulpitis were observed in specimens treated with Osteogen or Dycal. Reparative dentin formation along the pulp walls was also seen. After 14 days the pulpitis was more extensive in the Osteogen-treated teeth than in the control teeth. Dentin formation as measured by morphometric analysis was more pronounced in Osteogen-treated teeth. Neo-odontoblasts were observed after the use of both materials. After 28 days an acute inflammatory reaction was still evident in the Osteogen-treated group. A complete dentinal bridge was observed more frequently with Dycal than with Osteogen. Despite the putative abilities of HA to be osteoconductive, osteogenic, and dentinogenic, the results of this study indicate that it should not be used as a pulp-capping agent because of its tendency to cause scattered dystrophic calcification in the dental pulp, which could interfere with future endodontic treatment.

Animals↗
PubMed1991

Electron microscope characteristics of dentin repair after hydroxylapatite direct pulp capping in rats.

In order to study the osteogenic action of hydroxylapatite (HA) on the dental pulp, a pulp capping experiment was designed using the rat upper molar. Under general anesthesia, molar teeth in 14 male Sprague-Dawley rats were pulp capped with Osteogen (HA) or with Dycal as a control material. After pulp capping, the maxillary molars cavities were restored with amalgam and a pedodontic steel crown was adjusted and sealed over the molar teeth on either side of the maxilla. After 7 days, the areas of necrosis and acute inflammation were more evident in the pulps treated with Dycal than with Osteogen. Hard tissue formation began to appear around dentinal chips in the pulp and extended from the cavity walls into the pulp regardless of the material that was used. Furthermore, this calcified material was scattered throughout the pulp when Osteogen was used, but was not observed in the Dycal treated pulps. The hard tissue formation was thought to be due to the putative fibroblasts and odontoblasts found in the pulp. After 28 days dense dentinal tissue was observed bridging the exposure site when Dycal was used. The dentinal tissues formed with Osteogen was always of a globular type, and showed an irregular distribution. Since Osteogen tends to cause areas of dystrophic calcification in the pulp, its use is not be recommended for pulp capping purposes in humans, because these areas of calcification would make future endodontic treatment difficult.

Animals↗
PubMed1991

[Biocompatibility of dental materials. Choice of testing methods: to do or not].

Three methods used to study the biocompatibility of dental materials are compared in this article. A glass-ionomer cement, Vitrabond, was studied, using gutta-percha as the control material. Specimens were standardized according to an original procedure. Unsterilized Vitrabond implants were used, because UV rays modify the material. Intraperitoneal Vitrabond implants increased the macrophage population in rats after 24 hrs. This was caused by the surgical trauma and indicates that this method is unreliable. The intramuscular placement of Vitrabond provoked well defined lesions after a week. The use of histochemical techniques on frozen muscle demonstrated that the concentration of succinic deshydrogenase and acid phosphatase enzymes were altered when compared to the control lesions. A comparison of enzymatic lesions and an evaluation of the areas of cellular growth inhibition during in vitro experiments using a computer image analyzer leads to quantitative conclusions that Vitrabond is a cytotoxic material. The simultaneous use of histochemical techniques on muscle tissue and cell culture in vitro enhances the validity of methods used to evaluate the biocompatibility of dental materials. These methods may be used to test the toxicity of various materials. Nevertheless, for a more complete evaluation of these materials, the allergenicity and carcinogenicity potential of these products should be evaluated, prior to the final verdict as to their biocompatibility.

Animals↗
PubMed1990

Effect of hydroxyapatite on bone formation around exposed heads of titanium implants in rabbits.

Dense hydroxyapatite (HA)--collagen was placed around the protruding heads of titanium and titanium alloy implants in the femurs of 38 rabbits. After 6 months, bone apposition was evaluated by gross examination and scanning electron microscopy. Although bone was observed in direct contact with the implant heads, the extremities of the implant heads were surrounded by connective tissue. Compared with the control animals, packing dense HA-collagen around the implant heads did not increase the area of osteogenesis. When the implants penetrated into bone through previously placed HA-collagen blocks, there was a decrease in the amount of bone attached to the body of the implants compared with the controls. The results of this study suggest that the use of dense HA does not increase the amount of bone tissue formed around titanium implants.

Alloys↗
PubMed1990

[Facial asymmetry of nondental origin. Review and synthesis].

This article highlights a certain number of clinical conditions where one can encounter facial asymmetry. Among the many different etiological factors detailed are developmental anomalies, including those associated with under-development or over-development, asymmetry associated with trauma, as well as, those related to tumors. An in-depth analysis will allow a dentist to review differential diagnosis relative to asymmetry and note those within their competency level.

Facial Asymmetry↗
PubMed1990

[Oral manifestations of skin diseases].

There exists a multitude of systemic diseases which exhibit consequential oral manifestations. Dermatologic disorders frequently involve intraoral and perioral tissues which dental practitioners should be familiar with. A compilation of disorders including; bullous diseases (such as Pemphigus Vulgaris, Erythema Multiforme, Pemphigoid, Dermatitis Herpetiformis, Epidermolysis Bullosa, and Darier's disease), as well as non bullous diseases (such as Lichen Planus, Psoriasis, Lupus erythematosus, Scleroderma, and Perioral Dermatitis); and their oral manifestations are presented in order to facilitate their early diagnosis and subsequent treatment.

Darier Disease↗
PubMed1989

[Granuloma or cyst? The unknown chronic periapical lesion].

The periapical lesions, granuloma and cyst, are being dealt with in modern scientific articles. The ethiology, whether it be infectious, traumatic, physical or chemical, is reviewed and mention is made of the fact that pulpal necrosis or gangrene is a prerequisite for these chronic proliferous lesions. According to epidemiological studies, the granuloma is observed more often than the cyst and the cyst more often in the upper jaw bone. Furthermore, certain teeth show a particular susceptibility to one or the other of these lesions. An x-ray is not sufficient to assure the appropriate clinical diagnosis. Electrophoresis and histopathology does, however, allow one to do the same. Acting as an immunological entity, the granuloma is less of an immunological irritation than a local defense protective barrier.

Diagnosis, Differential↗
PubMed1989

[Oral manifestations of anorexia nervosa].

The oral manifestations of anorexia nervosa are presented with the help of published articles from the last fifteen years. After a brief history of the disease, the epidemiology and etiology are dealt with in detail. The clinical, systemic and oral symptoms are described. Finally, the various systemic, psychological and dental treatments are discussed.

Adolescent↗
PubMed1989

[The maxillo-mandibular desmoid fibroma. Synthesis of knowledge about a rare entity. Apropos of 3 cases].

Three cases of maxillo-mandibular desmoplastic fibroma are added to the 41 cases already described in the literature. A synthesis of the actual knowledge concerning the tumor is presented. The tumor is mainly composed of fibrous tissue with bundles of mature collagen, and can be easily confused with a low grade fibrosarcoma. Most of the patients are caucasian males. It is a young people tumor (0 to 30 years) with a peak between 6 to 15 years. The mandible was involved in 36 cases and the maxilla in 8 cases. The left side was involved in a ratio of 2 to 1 compared to the right side. In the mandible, the tumor was observed most frequently in the body and at the angle of the jaw. Pain or tumefaction were the most prevalent clinical features. The etiology of the tumor is unclear but trauma is often implicated. When the treatment is conservative, recurrences are frequent. The maxillo-mandibular desmoplastic fibroma should be recognized early to avoid local tissue destruction.

Adolescent↗
PubMed1988

[Burkitt's lymphoma. Survey and current data].

The non endemic Burkitt lymphoma is compared to the endemic type with the help of the pertinent literature. A series of 9 cases of Burkitt lymphomas which were treated and retrieved during a 18 year period at the Notre-Dame Hospital of Montreal is presented. Some possibilities of viral propagation through the dental pulp to the bone are explained.

Adult↗
PubMed1984

Morphologic changes of the esophageal mucosa in the rat after chronic alcohol ingestion.

Fifteen litter-matched pairs of Sprague-Dawley rats were divided into two groups, one fed an alcoholic diet and the other fed an isocaloric but non-alcoholic diet. 5 animals each of the experimental and control groups were sacrificed at 98, 200 and 290 d. The upper part of esophagus was fixed for morphological analysis of semi-fine sections. The following histological observations were made on the oral-esophageal mucosa of the alcohol-consuming animals: An epithelial atrophy was observed between 200 and 290 d of alcoholisation . This atrophy was not the result of a decrease in the number of epithelial layers, but was associated with a decrease in basal cellular size. A basal cell pleomorphism and a tendency towards epithelial dysplasia were the rule after long time alcohol consumption. These observations reflect features resembling to those seen in Plummer- Vinson syndrome, a precancerous state in humans.

Alcoholism↗