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C Maruyama

Publications and source records attributed to C Maruyama.

35 records · Page 2Linked to original sources
PubMed1990

[A case of Borrmann type 4 colon cancer with a metastasis into hepatoma].

A rare case of a colon cancer with a hepatomatous metastasis is reported. A 79 year old female was admitted hospital in April, 1988 with liver cirrhosis. On death in November, 1988, an autopsy revealed a primary, linitis plastica type diffuse adenocarcinoma of the total colon with an extensive metastases into lungs, kidneys, liver, small intestine, bladder, spleen, the bone marrow, and the lymph nodes. In the cirrhotic liver two hepatomatous nodules were found. As a focus of one of these nodules, there was a metastatic linitis plastica lesion of the colon.

Adenocarcinoma, Scirrhous↗
PubMed1988

[A case of signet-ring cell type cancer of the colon].

A rare case of a primary signet-ring cell carcinoma of the sigmoid colon in a 66-year-old man is reported. Endoscopically, a sessile polyp, 2 cm in diameter, was found in sigmoid colon, consisting mainly of a well differentiated adenocarcinoma and, partially of a signet-ring cell carcinoma. A residual polyp was found at the same site in the sigmoid colon, sixth months after surgery. The resected polyp was histologically confirmed as being a signet-ring cell carcinoma, which had infiltrated into submucosal space by scirrhous invasion. After a polypectomy, a partial colectomy was performed and no carcinoma cells have been identified in the resected colon. We have speculated that this signet-ring cell polyp could develop into Borrmann type 4 advanced colon cancer.

Adenocarcinoma↗
PubMed1988

[Histochemical analysis of uterine cervical adenocarcinoma with reference to mucosubstances and distribution of CEA, CA125 and CA19-9].

Epithelial mucin and immunohistochemical localization of carbohydrate antigens (CA125, CA19-9) in normal endocervical glands and adenocarcinoma of uterine cervix were examined histochemically. The materials were obtained from 33 surgical cases with adenocarcinoma and 9 control cases. Serial sections were examined by the following procedures: 1) Digestive PAS reaction, 2) High iron diamine-Alcian blue pH 2.5 staining, 3) Modification PAS and Thionin Schiff reaction to differentiate sialic acid, 4) Immuno-peroxidase method. Histologically, these adenocarcinomas were classified into four subtypes, endocervical, intestinal, endometrioid and serous adenocarcinoma. Endocervical adenocarcinomas were differentiated into the endocervical-intestinal group and serous-endometrioid group by mucin profiles and distribution of carbohydrate antigens. In endocervical and intestinal types, sialomucin was predominant, this mucin being characterized by O-acetylated sialic acid. Immunohistochemically, CA19-9, CA125 and CEA were localized in this group. The latter group of tumors were serous and endometrioid adenocarcinomas, characterized by surface coat type sulphomucin and non-acetylated sialic acid, but CA19-9 and CA125 were not detected in these cases. Adenoma malignum was classified in endocervical type adenocarcinoma.

Adenocarcinoma↗
PubMed1985

[Clinical trial of aztreonam in the field of obstetrics and gynecology].

Clinical effect and safety of aztreonam (AZT) in the obstetrics and gynecology were studied in 17 cases of obstetric and gynecological infections. AZT was administered at a dose of 2 g per day by intravenous drip infusion, for 4-8 days depending on severity of the disease. The results showed that AZT was effective in 14 out of 17 cases and the overall efficacy rate was 82.4%. E. coli, Enterobacter, E. faecalis, etc. were detected in 8 out of 17 cases, and after AZT treatment other strains appeared in 3 clinically effective cases. There was a slight elevation of GOT and GPT in 1 case but no other appreciable side effect or abnormal laboratory value was observed.

Adult↗
PubMed1985

[Results of the clinical use of cefminox in the field of obstetrics and gynecology].

Cefminox (CMNX, MT-141) was used in the treatment of obstetrical and gynecological infections with following results. In the treatment of a total of 8 cases including 4 cases of intrauterine infections, 2 cases of pyosalpinx and 2 cases of pelvioperitonitis, clinical results obtained were rated as excellent in 4 cases (50%) and good in 2 cases (25%). When good and excellent results were combined as representing effectiveness, the effective rate was 75% (6/8 cases). The 2 cases, which gave poor results, were under treatment for ovarian carcinoma. CMNX was found effective for intrauterine infections (postpartal) and pyosalpinx, especially those caused by E. coli. None of the cases experienced side effects.

Adult↗
PubMed1981

A case of metastatic lung cancer healed clinically with an extract from human tubercle bacilli (Maruyama vaccine--SSM).

1) A case of metastatic lung cancer derived from testicle is described which, in spite of continuing growth after the removal of the primary lesion, responded to the sole treatment of Maruyama vaccine (SSM) with completely satisfactory results and showed no recurrence over a period of 4 years. 2) The therapeutic course of the metastatic lung tumors in the present case showed a close correlation with the changes in the peripheral blood lymphocytes count and the alpha-2 globulin level. 3) The course of the response of the metastatic lung foci to the SSM therapy could be summarized as continued increase of tumors in size and number for the first 3 months, followed by shrinking, disappearance, and finally healing.

Adult↗
PubMedDate not supplied

Overexpression of human H-ras transgene is responsible for tumors induced by chemical carcinogens in mice.

Level of human prototype H-ras transgene expression in tumors induced by chemical carcinogens (N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea) was analyzed in human H-ras transgenic mice (CB6F1-TgrasH2 Jic mice). All forestomach tumors examined revealed about 2-fold overexpression of the human H-ras transgene with or without point mutation at codon 12 or codon 61. However, endogenous mouse H- and K-ras genes exhibited neither point mutation nor overexpression. These results suggested that increased levels of ras gene products in the cell played an important role in facilitating chemical carcinogenesis in transgenic mice.

Animals↗
PubMedDate not supplied

Right side hepatic resection under right thoracoabdominal incision with special reference to a highly anatomical systematized method.

The results of 31 right side hepatic resections approached through thoracoabdominal incision are described, with emphasis on the benefit of the approach and systematized liver resection. Regarding postoperative mortality rate (0%) and morbidity rate (32.3%), the thoracoabdominal approach for right side hepatic resection seemed as safe and effective as the conventional abdominal approach. Even though there were no significant differences in the complications, the fluctuation of alanine aminotransferase and the hospital stay, the average operation time for the right segmentectomy through the thoracoabdominal approach was 1.3 hours less (p = 0.0078) than that of the abdominal approach. Technically, this approach was accomplished in almost the same fashion as in the abdominal approach by the utilization of systematized hepatic resection. Thoracotomy itself was not more harmful than the abdominal approach, even in patients with impaired liver function. This combination could take the advantage of a shorter operation time.

Adult↗