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C Marchelli

Publications and source records attributed to C Marchelli.

4 recordsLinked to original sources

Escherichia coli K-12 gyrB gene product is involved in the lethal effect of the ligts2 mutant of bacteriophage Mu.

Mu ligts2 mutants, defective for development and integration, show a high killing effect on the infected host. A number of survivors to Mu ligts2 infection were analyzed; they are characterized by nonpermissivity for both development and lysogenization of bacteriophage Mu. Bacteriophages D108 and P1 are also inhibited in these strains as is transposon Tn9. The corresponding mutation site was mapped at 82 min and identified with the Escherichia coli gyrB site.

Coliphages

Deletions induced by heat treatment of E. coli K12 lysogenic for lambda prophages.

We have investigated the production of prophage deletions in heat-induced lambda lysogens of E. coli K12. Our results are indicative of a direct action of the heat-induced prophage in producing deletions. The temperature of 40 degrees used for the experiments may be critical to prove this effect. The phage function involved in deletion formation is not known.

Chromosome Aberrations