Biomedical subjects

C Marcelli

Publications and source records attributed to C Marcelli.

57 records · Page 4Linked to original sources

PubMedDate not supplied

Acute sacroiliitis as a manifestation of calcium pyrophosphate dihydrate crystal deposition disease. A report of two cases.

Whereas radiographic lesions of the sacroiliac joints are common in patients with calcium pyrophosphate deposition crystal disease, they are rarely accompanied with clinical symptoms. We report two cases of acute sacroiliitis probably due to calcium pyrophosphate dihydrate deposition disease. The patients were a 53-year-old man and an 82-year-old woman with chondrocalcinosis in other joints and presence on computed tomography studies of the sacroiliac joints of sclerosis and irregularities of the joint margins with a thin linear calcific deposit within the joint. Both patients recovered fully under therapy with colchicine, analgesics and rest. These two cases suggest that acute sacroiliitis can be caused by calcium pyrophosphate dihydrate crystal deposition disease.

Acute Disease↗

PubMedDate not supplied

Cerebral vein thrombosis after an intrathecal glucocorticoid injection.

We report two cases of cerebral venous thrombosis that occurred after an intrathecal glucocorticoid injection for common lumbosciatic syndrome. The patients were two females, aged 34 and 47 years, who developed typical post-lumbar puncture headache. The manifestations leading to the diagnosis of cerebral venous thrombosis were status epilepticus in one case and persistent headache in the other. Both patients were using oral contraceptives. Grynblat et al. (Rev Rhum [Engl Ed] 1995; 62: 691) recently reported two cases in young women of cerebral venous thrombosis after intrathecal administration of a glucocorticoid or an iodinated contrast agent. These cases are useful reminders that intrathecal glucocorticoid injections can be followed by cerebral venous thrombosis, and that younger women may be at increased risk for this complication.

Adult↗

PubMedDate not supplied

Contribution of laboratory tests, scintigraphy, and histology to the diagnosis of lower limb joint replacement infection.

OBJECTIVE: To evaluate the contribution of laboratory tests, histology and scintigraphy for diagnosing and monitoring the treatment of lower limb arthroplasty infection. PATIENTS AND METHODS: 37 lower limb arthroplasties, 20 at the hip and 17 at the knee, were studied. Investigations included laboratory tests for inflammation (erythrocyte sedimentation rate, C-reactive protein, haptoglobin, and orosomucoid), histology (presence of neutrophils) and scintigraphy (99m Tc-HMDP bone scan, colloidal sulfide bone marrow scan, and 99m Tc-HMPAO leukocyte scan). Follow-up was at least three years after treatment of the infection. RESULTS: Acute phase reactants were more sensitive and more specific than the erythrocyte sedimentation rate. The full scintigraphy protocol had 100% sensitivity and 87% specificity. Recovery of neutrophils by aspiration or during surgery was 100% specific in the absence of hematomas or rheumatoid arthritis. Sensitivity of the presence of neutrophils varied with the collection technique.

Adult↗