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Biomedical subjects

C Maiolo

Publications and source records attributed to C Maiolo.

22 records · Page 2Linked to original sources

Orolaryngeal sarcoidosis presenting as obstructive sleep apnoea.

A 53-year-old man was evaluated for snoring, dysphagia for solid foods and difficulty of breathing and a polysomnographic recording was consistent with a diagnosis of obstructive sleep apnoea syndrome (OSAS). A flexible fiberoptic bronchoscopy (FFB) showed the presence of a nodular lesion of the posterior ventral surface of the tongue strictly connected to the left lateral border of the epiglottis. The biopsy specimen taken from the lesion was consistent with sarcoidosis. No involvement of pulmonary parenchyma, lymph nodes or other organs was recognized. After two months of steroid treatment, symptoms disappeared and resolution of the nodular lesion at the FFB and normalization of the polysomnographic recording were observed. This is the first report of orolaryngeal sarcoidosis associated with OSAS as the only clinical presentation of the disease.

Bronchoscopy↗

Accuracy of indirect estimation of oxyhaemoglobin saturation in patients with respiratory failure.

The indirect estimate of oxyhaemoglobin saturation (Sa,O2) is largely used in the management of patients with respiratory failure. The aim of this study was to evaluate the accuracy of the Sa,O2 values calculated by using both the Siggaard-Andersen (SA) and the Severinghaus (SE) equation, in comparison with the real Sa,O2 values measured by a co-oximeter. A total of 558 arterial blood samples were analysed. On average, only a slight overestimation was found for Sa,O2 estimated by the SA (2.35 +/- 5.75%) and the SE (2.37 +/- 5.65%) equations in comparison with the real values. However, a difference higher than 5% between estimated and real Sa,O2 values was demonstrated in more than 20% of the blood samples evaluated. This difference was higher than 10% in 9% of the samples, with similar results obtained with the two equations. The discrepancy between real and estimated values, probably due, at least in part, to errors in measurement of arterial oxygen tension (Pa,O2) and pH, was maximally evident for Sa,O2 values lower than 70%. An indirect estimate of Sa,O2 is not homogeneously accurate, and the clinical consequence of this finding might be especially dangerous in monitoring patients with severe respiratory failure.

Humans↗

Variation in condensation pressure during clinical packing of amalgam restorations.

Clinical measurements were made of the condensation pressures applied by a specialist prosthodontist to each amalgam increment during the packing of two pinned Class II restorations. The technique employed involved taking simultaneous video recordings of the operative procedures and the output of a strain gauge stress measuring system attached to the plugger. The condensation pressure applied during each thrust of the plugger could then be related directly to a particular stage of the packing process. In Cavity A, a maxillary left second premolar, an "admix" amalgam containing both spherical and lathe-cut particles was used while Cavity B, a mandibular right first molar, was filled with a spherical particle amalgam. The measurements indicated that the condensation pressures applied decreased substantially as the filling of each cavity proceeded. A marked reduction accompanied the change from a 1.5 mm diameter to a 2.5 mm diameter plugger but in addition, the dentist modified the force applied to each plugger according to the particular task which he was undertaking. For Cavity A, the condensation pressure applied during the filling of the base of the mesial proximal box was 12.6 +/- 1.9 MPa whereas the final increment was subjected to a condensation pressure of only 2.2 +/- 0.7 MPa. Corresponding figures for Cavity B were 7.6 +/- 2.0 MPa and 1.9 +/- 0.5 MPa.

Dental Alloys↗

[Guidelines and malpractice in obesity treatment].

BACKGROUND: Obesity, is one of the most common nutritional disorder in developed countries. The association with several health disorders (i.e., type 2 diabetes mellitus, hypertension, hyperlipidemias, cholelithiasis, obstructive sleep apneas, coronary heart disease, cancer) is frequently present. DESIGN: Obesity is, actually, measured using body mass index (BMI) determination. However, BMI isn't useful to predict body fat content. Skin-fold thickness, bioelectrical impedance analysis and/or dual energy x ray absorptiometry are specific tools with different capability to measure body composition (i.e., fat mass and fat-free mass). All these methods need a large data-base of age, sex and population reference values. CONCLUSIONS: Obesity management (dietary treatment, monitoring of weight loss, pharmacologic approach, and surgery ) is associated with several complications and errors.

Absorptiometry, Photon↗