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Biomedical subjects

C M Silva

Publications and source records attributed to C M Silva.

48 records · Page 3Linked to original sources

[The coconut babaçu (Orbignya phalerata martins) as a probable risk of human infection by the agent of chromoblastomycosis in the State of Maranhão, Brazil].

During a survey of 30 patients with chromoblastomycosis followed at the Hospital dos Servidores do Estado do Maranhão, the authors observed in 2 (6.6%) patients with lesions on the buttock. This is an uncommon site for the initial lesions of chromoblastomycosis. There is often a history of microtraumatism during the farming job hence the more frequent development of lesions in the lower limbs. Both patients had 10 years disease, with the presence of nodules and vegetant warty lesions in coalescent plaques on the right buttock. Etiologic diagnosis made through histopatologic and culture exams, with Fonsecaea pedrosoi isolated. The epidemiological exposure of the patients, was suggested by the fact that both worked as babaçu coconut cutters a common activity in Maranhão State. The relation between this kind of professional activity and the development of infection merits for the investigation.

Agricultural Workers' Diseases↗

Some environmental and biological factors influencing the activity of entomopathogenic Bacillus on mosquito larvae in Brazil.

The influence of environmental and biological factors on the efficacy of Bacillus thuringiensis serovar israelensis and B. sphaericus as mosquito larvicides are reviewed. The importance of strain dependence, cultivating media/methods, mosquito species/specificity, formulations and their relation to mosquito feeding habits, as well as temperature, solar exposure, larval density and concomitant presence of other aquatic organisms are addressed with reference to the present status of knowledge in Brazil.

Animals↗

[Evaluation of outpatient care for people with HIV/AIDS in Rio de Janeiro, from the user's perspective].

This article analyzes perceptions by people with HIV/AIDS towards five specialized units under the State Health Department, Rio de Janeiro, concerning the care provided there. The research was based on both quantitative and qualitative methods. Data from 228 questionnaires and 19 semi-structured interviews were analyzed. The results generally indicated a positive evaluation on the part of this group of health care users. One conclusion was that the positive evaluation was actually related to the quality of the services available to them. However, users seem to have low expectations toward the level of services public clinics generally provide.

Acquired Immunodeficiency Syndrome↗

[Characterization of the cases of domestic violence against women assisted in 2 public hospitals of Rio de Janeiro].

This paper aims at: (a) to analyze the distribution of the cases of domestic violence against women (adolescent and adult) in relation to emergency care due to external causes; (b) to characterize the victims and the rendered care; (c) to analyze the circumstances in which events happened. In methodological terms, it tries to articulate the quantitative and qualitative approaches. The study was developed in two public hospitals of reference placed in the city of Rio de Janeiro. Of the 72 assisted women, most referred to the husband, the partner or the boyfriend as the aggressor (69.4%) and were beaten (70.4%) especially on the face and on the head. The study comes to the conclusion that the health services should provide a good clinical care and promote prevention's actions.

Adolescent↗

[Giant hemangioma treated with interferon alpha-2a].

OBJECTIVE: The authors describe a case of giant hemangioma treated with interferon alpha-2a and review the role of this drug and other therapeutic modalities in the management of vascular lesions. METHODS: A seven month-old child with giant hemangioma and persistent bleeding, anemia and repeated infections was treated with interferon alpha-2a. The drug was administered at the dosage of 3 million units/m(2)/day, subcutaneously, for nine months. RESULTS: Response to treatment was considered excellent, with regression of 90% of the lesion, control of bleeding, infection and anemia, and catch-up growth. No untoward effects were observed. CONCLUSION: Interferon alpha-2a should be considered as a valid therapeutic option in selected cases of hemangioma in children.

English Abstract↗

Genetic and environmental influences on atopic immune response in early life.

The purpose of our study was to carry out a prospective follow-up of 114 newborns at term (including three pairs of twins), regarding clinical manifestations for atopy during the first year of life. Their IgE levels in cord blood samples, at 3, 6, 9 and 12 months of age were measured and the influence of race, sex, breast-feeding, maternal smoking, family income, month of birth, family history and personal manifestations of atopic disease were evaluated. Total serum immunoglobulin E was quantified by microparticle enzyme immuno-assay (MEIA). The study group consisted of 60 (53%) male neonates, 67 (59%) Caucasians and 47 (41%) blacks. In the clinical follow-up, 32 (28.1%) infants developed obvious atopic disease: 29 infants presented recurrent wheezing, two had cow's milk allergy and one had atopic dermatitis. Probable atopic disease developed in 12 (10.5%) infants, whereas 70 (61.4%) infants showed no manifestations. Cord blood IgE levels in infants with obvious atopic disease was higher when compared to those without (p = 0.024), with 70.97% sensitivity and 46.2% specificity. IgE levels were also significantly different up to 12 months in these groups (p = 0.0001), when the sensitivity was 82.1% and the specificity 54.1%. At this age, the IgE levels were higher in infants with obvious atopy than nonatopic disease in relation to male sex (p = 0.015), black race (p = 0.009), breast-feeding for less than 6 months (p = 0.011) and when the family income was less than three times the minimum wage (about US $300) (p = 0.006). There was no association between IgE levels and family history of atopy. We concluded that immune response for atopy was in a large degree influenced by environmental factors and serum IgE at 12 months was a good marker for identifying infants with risk of atopic disease in early life.

Breast Feeding↗

[Predictive value of reactive strips in urinary infection].

The microbiologic method to confirm or not the diagnosis of urinary tract infection is usually the culture and Gram-stain of the clean-catch midstream urine. Nevertheless, this is a costly and time-consuming method. We tried to evaluate the positive and negative predictive value of the nitrite and leucocyte-esterase reactive strips as an alternative method. When both the two parameters are negative it is fairly safe to exclude the urinary tract infection.

Humans↗