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Biomedical subjects

C M Papa

Publications and source records attributed to C M Papa.

At least 37 records · Page 2Linked to original sources

Pectoralis muscle shortening and rigor development at different locations within the broiler breast.

Two experiments were conducted to evaluate differences in rigor development that occur as a function of location within the broiler breast muscles, pectoralis major (p. major) and pectoralis minor (p. minor). Three locations were evaluated, corresponding to anterior, middle, and posterior samples taken between the cranial and caudal ends of each muscle. Results of the first experiment indicated that the 1.55-mu sarcomere lengths of hot-boned p. major muscle at the anterior location were significantly shorter than those at the posterior location, which were 1.69 mu. Sarcomere lengths of p. minor were shorter than those of p. major in hot-boned muscles, but longer in those aged intact, indicating a significant muscle x treatment interaction. In the second experiment, the anterior location of hot-boned p. major reached the onset phase of rigor in about 1 h, whereas those at the posterior location required between 2 and 4 h postmortem. Between 1 and 8 h postmortem, sarcomere lengths for the anterior location of p. major were also significantly shorter than lengths in the posterior location, but the differences after 24 h were not significant. Samples at all locations of p. minor reached onset of rigor by 15 to 30 min postmortem, with no locational differences throughout the 24 h period of aging. The results of both experiments generally indicated differences between profiles of rigor development of the two muscles and between samples at different locations of the much larger and more complex p. major.

Animals↗

Tinea versicolor: a scanning electron microscopic view.

Tinea versicolor (TV) infections were studied in the scanning electron microscope utilizing several different sampling and preparatory techniques. Scalpel scrapings provided information only on the morphology of individual spores and hyphae, while biopsies and cyanoacrylate adhesive slides demonstrated the topography of the disease as well as providing information on how the infection spreads and recurs. Critical point drying was necessart to maintain the fine ultrastructure previously described. The deep follicular location of the spores seen in this study probably explains the tendency for TV to recur. The follicular packing was specific, since the eccrine pores seem to be exempt from the infection.

Humans↗

Scanning electron microscopic study of tretinoin (vitamin A acid) acne therapy.

Structural differences between untreated and tretinoin treated acne, uniquely evident with the scanning electron microscope, provide insight into the disease and its response to the drug. Early tretinoin therapy is characterized by the appearance of loosely adherent, parakeratotic cells which account for comedo expulsion and a disrupted skin surface. Persistence of the follicular and comedonal alterations account for the prophylactic value of long-term therapy. Meanwhile, the structure of the stratum corneum returns toward normal, with the clinical accommodation to the topical tretinoin.

Acne Vulgaris↗