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Biomedical subjects

C M Lostao

Publications and source records attributed to C M Lostao.

24 records · Page 2Linked to original sources

A cline in the acid phosphatase1 distribution in the Iberian Peninsula.

Blood samples from autochthonous and unrelated persons were examined for acid phosphatase (ACP1) phenotypes. The subjects were 143 Spanish Basques, 118 people from León and 295 from Castile. The samples were typed using starch gels, with one surface coloured with phenolphthalein diphosphate (Na5 salt) and the other surface revealed with 4-methylumbelliferyl-dihydrogenphosphate. The gene frequencies observed are compared with those obtained by other authors.

Acid Phosphatase↗

Some red cell enzymes and haptoglobin gene frequencies in two Basque regions and León.

A study was conducted to determine the distribution of phenotypes and gene frequencies of haptoglobin, phosphoglucomutase 1, esterase D, 6-phosphogluconate dehydrogenase and three monomorphic systems SOD, sMDH and NADH DIA I. Results obtained from two Basque regions and León were compared with those from other Spanish populations. Gene frequencies observed in the León sample were similar to those obtained from the other Spanish samples. The Basque samples differed from the other Spanish populations in the gene frequencies of esterase D.

Carboxylesterase↗

Some genetic markers in Castillian populations.

Haptoglobin, phosphoglucomutase 1 and 6-phosphogluconate dehydrogenase gene frequencies have been found for some Castillian provinces. The NADH diaphorase I, superoxide dismutase, lactate dehydrogenase, soluble oxaloacetate transaminase, soluble malate dehydrogenase, carbonic anhydrase I and carbonic anhydrase II are non-polymorphic red cell enzymes in Caucasoids and we have verified this in Castillian samples.

Gene Frequency↗

Finger ridge count in Basque populations: univariate and multivariate comparison with other Spanish populations.

We have analysed finger ridge counts in the indigenous Spanish Basque population (841 males and 911 females). Bimanual and sexual variation have proved to be statistically significant. The results in the Basque population were compared with those of other Spanish populations. In the univariate comparison statistically significant differences appear. The means found in the Basque population are the lowest. Our population is situated on the lower part of the variation range of the European populations for whom data are available. In principal component analysis the first two components explain more than 90% of the total variability. The first component is interpreted as a size component, which is usual. The factor scores of the individual samples have proved to be very useful in showing which populations are nearest to the Basque one.

Dermatoglyphics↗

Characterization of digital dermatoglyphic features in Salazar Valley: comparison with other Basque valleys.

Digital dermatoglyphics of a sample from the Basque Valley of Salazar, situated in the West of the Pyrenees, were analysed. The results showed bimanual differences in both sexes, and also sexual differences for both hands. The comparative study with other Basque valleys showed that, in spite of their supposed common origin, the geographic barriers and the isolation have generated a genetic/dermatoglyphic and linguistic differentiation.

Analysis of Variance↗

Fluctuating dermatoglyphic asymmetry: genetic and prenatal influences.

Genetic and environmental prenatal factors influencing the fluctuating asymmetry of the a-b interdigital ridge count are examined. From the results obtained we can conclude that fluctuating asymmetry of the a-b interdigital ridge count is poorly influenced by genetic factors. We suggest that fluctuating asymmetry of dermatoglyphics provides a good measure of developmental stability in humans, especially for males. The results also indicate that random environmental factors, acting before the 19th week of embryonic development, could be related to the differential timing of maturation of the sexes.

Dermatoglyphics↗