A program to introduce medical students to the problem of child abuse and neglect.
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Child↗
Biomedical subjects
C M Hansen
Publications and source records attributed to C M Hansen.
Effects on pregnant adolescents of attending a special school.
Data on nutrient intakes and blood vitamin levels were obtained for twenty-nine pregnant adolescents attending a special school for pregnant school-age girls in New Brunswick, New Jersey. Except for calcium and iron, mean intakes were equal to or greater than the Recommended Dietary Allowances. Food eaten at school contributed 35 to 43% of the total nutrient intake. Mean blood vitamin levels were normal to high, although about a fourth of the girls had low levels of vitamin B6 and folate. All except one delivered normal, full-term infants. It was concluded that attendance at such a special school contributes to normal pregnancy outcome among teen-age mothers.
Adolescent↗
Editorial: Physician responsibility in child abuse.
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Child↗
The pediatric nurse practitioner in the private office.
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Female↗
The pediatrician and family planning in a very poor community. An appraisal of experiences in the Tufts Delta Health Center, Bolivar County, Mississippi.
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Adolescent↗
Child health problems and programmes in two underdeveloped areas of the USA.
There are areas in the USA where the health problems of children a similar to those of children in some developing countries. Traditional US health programmes have contributed to an improvement in the health status of many of these children but there remains much more to be done.
Child↗
Cyanoguanidine CHS 828 induces programmed cell death with apoptotic features in human breast cancer cells in vitro.
The cyanoguanidine CHS 828 was recently shown to possess potent anti-tumour effects both in vitro and in vivo. The exact mechanism of action of CHS 828 is not known, but recent results have indicated that induction of programmed cell death may be one mechanism by which CHS 828 exerts its anti-tumour effects. To investigate this aspect in more detail, we studied the effect of CHS 828 and the reference compound Taxol beta on programmed cell death in human breast cancer cells in vitro. Both compounds were found to induce DNA fragmentation in the cells. However, microscopic examination of the cells demonstrated that CHS 828 and Taxol triggered different types of cell death. In the CHS 828-treated cultures most cells were found to be Annexin-V positive, indicating that these cells were early apoptotic cells, while no morphological characteristics of classical apoptosis were seen. In contrast, the cells in the Taxol-treated cultures displayed morphological features characteristic of classical apoptotic cells, but no Annexin-V positive cells could be observed. These findings together with the previously reported potent effects of CHS 828 on tumour cells, makes CHS 828 a promising new agent for the treatment of cancer patients.
Annexin A5↗
Can we protect children from abuse? A review of three cases.
Abused infants at risk of further abuse are not being protected for many reasons. The ability of a variety of professionals to recognize and manage abuse when it occurs is limited. The reasons for this are briefly presented. Three cases in which young infants were reinjured, one fatally, are presented. Continuing efforts to improve all parts of the child welfare system and community response system need to be made. In this way, infants at risk will be better protected in our society.
Brain Injuries↗