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Biomedical subjects

C M Giles

Publications and source records attributed to C M Giles.

At least 73 records · Page 4Linked to original sources
PubMed1978

Fy (a-b-) phenotype in Czechoslovakia.

A family of gypsy origin, with 5 Fy(a-b-) members was found in Czechoslovakia. The involvement of the silen allele, Fy, in paternity testing is discussed.

Alleles↗
PubMed1976

The Vel blood group in northern Sweden.

Using the potent anti-Vel, Paul., a detailed study of the Vel blood group has been made in the Northern region of Sweden. Family studies have shown Vel to be independent of P1, though some association with P groups was detected since P2 was more frequent amongst Vel(-) than expected. The frequency of Vel(-) was 0.0006.

Blood Group Antigens↗
PubMed1976

Linkage relationships of the loci of the major histocompatibility complex in families with a recombination in the HLA region.

A number of families with an established recombination in the major histocompatibility complex has been investigated for markers known to be coded by genes of this linkage group. The results provide further data on the relative position of the loci for HLA-A, HLA-B, HLA-C, HLA-D, Bf, Chido, Rodgers and PGM3 on chromosome 6. A positive lodscore for linkage between HLA and blood group P was found; lodscores between HLA and nineteen other markers were negative.

Chromosome Mapping↗
PubMed1976

Rga (Rodgers) and the HLA region: linkage and associations.

In 19 families with 97 children the segregation of Rga (Rodgers) was found to be compatible with Mendelian inheritance and five backcross and 14 intercross families were found among HLA and Bf typed families. Close linkage (lods + 17.82) without recombination was found between Rg and the HLA region, with a direct count of 96 nonrecombinant meioses for Rg-HLA-B. Rg- was strongly associated with HLA-B8 (29 of 30 haplotypes) and probably associated with Bw40, but did occur on other HLA-B haplotypes. By inference Rg- is negatively associated with Ch- (Chido). The Rg-Ch- haplotype has not been observed. Rga and Cha may or may not be coded for by different sites of the same cistron closely linked to HLA-B:C and cannot as yet be excluded from being parts of B or C.

Blood Group Antigens↗
PubMed1975

Antithetica+ relationship of anti-In-a with the Salis antibody.

Evidence is presented for the antithetical relationship of In-a with a previously unreported high frequency antigen, Salis. Three Salis (-) propositi were all found to be In(a+), and, although tested in London, came from the Indian subcontinent where the In-a antigen was first detected.

ABO Blood-Group System↗
PubMed1975

A new antigen Yk-a (York), and its relationship to Cs-a (Cost).

The antigen Yk-a is detected in 92 and 98% of the American Caucasian and Negro populations, respectively. In population studies with anti-Yk-a and anti-Cs-a, association was demonstrated between the two antigens; however, in two of three informative families Yk-a and Cs-a segregated independently. The possibility that these antigens have a relationship with leucocyte antigens is discussed.

Black People↗