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C Lefebvre

Publications and source records attributed to C Lefebvre.

100 records · Page 6Linked to original sources
PubMedDate not supplied

Three-year follow-up of Pawtucket Heart Health's community-based weight loss programs.

PURPOSE: The purpose of the study was to evaluate the effectiveness of a community-based weight loss program. DESIGN: A questionnaire was administered by telephone to subjects one to three years following participation in a weight loss program. SETTING: The study took place in Pawtucket, Rhode Island. The Pawtucket Heart Health Program is part of this setting. SUBJECTS: A stratified sample of 400 subjects was randomly selected from 2,186 people who participated in weight loss programs between 1985 and 1987. A total of 285 subjects completed the questionnaire; 229 subjects provided sufficient information to be included in the study. INTERVENTION: The subjects participated in community-based and worksite-based weight loss programs. MEASURES: Self-reported heights and weights before and after intervention and demographic data were collected. Desirable body weight and Garrow's health risk classifications were calculated. RESULTS: Overall, there was a 3.2% reduction in body weight between time of entrance into weight loss programs and time of interview. Eighty percent of the participants lost weight in the program; mean weight loss was 11 pounds. At time of follow-up interview one to three years later, 65% of subjects weighed less than at entrance into the community programs; on average, subjects weighed six pounds less. Sixty-nine percent of the sample was above 20% desirable body weight at entrance and 26% of this group lost enough weight to lower their health risk category. CONCLUSIONS: Weight loss in this community-based program compares favorably with those reported by more intense and expensive clinic-bound programs.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMedDate not supplied

[Color echo-Doppler and endometrial receptivity in in vitro fertilization].

The chances of nidation after in vitro fertilization procedures are contingent upon the development potential of the transferred embryo(s), but they also depend on the receptivity of the endometrium and on the uterine vascular supply. It is generally accepted that the chances of pregnancy are practically nil: if the endometrium is less than 8 mm thick, and/or if the uterine pulsatility index (PI) is below 3. However, the predictive value of the Doppler evaluation alone is poor to the extent that other parameters require consideration, such as the aspect of the endometrium and/or the number of embryos transferred. This is why our group initiated a prospective study on 213 patients designed to validate a 10 point scale based on: -the PI of each uterine artery on the day of transfer; -the features of the protodiastolic notch (absent, moderate or clearcut); -the thickness of the endometrium; -the number of embryos transferred. Each parameter by itself had a poor predictive value: optimal values of endometrium thickness and pulsatility index (PI) predicted a 29% and 33% pregnancy rate, which is hardly higher than our overall pregnancy rate (24%). By contrast, a score that encompasses all these parameters increased predictive value, with a score > 9 the probability of pregnancy reach 53% and the one of multiple pregnancy 24%. Our results emphasize the usefulness of a score prior embryo transfer which should be used to adjust the number of embryos transferred. When the score is higher than 10 transferring 2 embryos will prevent the risk of multiple pregnancy. 3 embryos should be transferred when the score is between 7 and 10, and a bad score (< or = 6) should delay the transfer.

Adult↗