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C Le Hello

Publications and source records attributed to C Le Hello.

6 recordsLinked to original sources

[Vasculitis associated with antiviral vaccines and antiviral agents].

There is firm evidence that several viruses can cause systemic vasculitis. Vasculitis induced by antiviral vaccines and drugs is less common and less well know. Most cases consist in de novo vasculitis that resolves spontaneously or under steroid therapy. Thus, the outcome is usually favorable. If an antiviral drug is the cause, it should not be used again in the patient. Another common sense measure is to refrain from immunizing patients with active vasculitis. A recent history of antiviral immunization or antiviral drug treatment should be sought routinely as part of the etiologic work-up of every patient with vasculitis.

Acyclovir

[Coronary revascularization provides confirmation of coronary and aortic giant-cell vasculitis].

The present report describes a 58-year-old woman who had unstable angina pectoris 28 months after the end of corticosteroid treatment prescribed for biopsy-proven temporal arteritis. Coronary angiogram disclosed critical left main coronary artery stenosis. Despite a 3-week corticosteroid regimen no improvement was obtained and an aortocoronary bypass was performed. Histological examination of the affected artery showed vasculitis. Corticosteroid treatment was continued. Six months later, symptoms had not recurred and the coronary bypass graft was permeable. The stress test was negative fifteen months after surgery and the patient remained clinically well thirty months later. For any patient with current or previous temporal arteritis, any cardiovascular manifestation might be a new episode of giant-cell arteritis.

Adrenal Cortex Hormones

Suspected hepatitis B vaccination related vasculitis.

Recombinant hepatitis B vaccination is widely used and severe side effects are rare. We describe 3 cases of vasculitis occurring after such immunization that are thought to have been vaccine induced. Vasculitides are now recognized as possible severe adverse side effects of immunization.

Adolescent

[Colchicine].

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Colchicine

[Orthotopic liver transplantation for metastases of bronchial carcinoid tumor].

We report the case of a 42 year old man in whom orthotopic liver transplantation was performed successfully for unresectable hepatic metastases of a bronchial carcinoid tumor. Prior to transplantation, somatostatin therapy, pulmonary lobectomy, and systemic chemotherapy (streptozotocin and fluorouracil) were performed. After 9 months there were no signs of clinical or biological recurrence. Orthotopic liver transplantation might be indicated for unresectable and limited liver metastases of neuroendocrine tumor.

Adult