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Biomedical subjects

C Lavalle

Publications and source records attributed to C Lavalle.

59 records · Page 4Linked to original sources

Gonadotropins pituitary secretion in systemic lupus erythematosus.

Hormonal abnormalities have been suggested to play a role in the pathogenesis of systemic lupus erythematosus (SLE). In order to define the regulatory mechanism involved, the pituitary reserve for gonadotropins secretion was investigated in eight untreated SLE patients with normal menstrual cycles. Serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were determined on the fifth day of the menstrual cycle before and after intravenous administration of 25 micrograms synthetic luteinizing hormone-releasing hormone (LH-RH). The pulsatile LH and FSH resting values in SLE were not significantly higher than those found in the controls; after LH-RH stimulation no difference was observed between the SLE group and controls. The LH and FSH response to exogenous LH-RH administration in SLE demonstrate the integrity of the hypothalamic-pituitary-ovary axis that explains normal menses and fertility in this disease.

Adolescent↗

[Reynold's syndrome. A case report (author's transl)].

One case of the association of primary biliar cirrhosis and systemic sclerosis progressive (SSP) is described (Reynold's syndrome). This association has been reported in 21 patients. In our case the signs of liver disease precede two years the appearence of SSP. A review of the patients with Reynold's syndrome reported is done and compared with the present case. Diagnostic approach and management of this association is also discussed.

Colchicine↗

Association of Behçet's syndrome with HLA-B5 in the Mexican mestizo population.

HLA typing done in 10 Mexican mestizo patients with Behcet's syndrome revealed that 7 of them had HLA-B5 antigen as compared to a frequency of 31% in a Mexican mestizo control population. These findings are akin to those made in Japan and Turkey but differ from those made in Caucasian populations in the United States and Great Britain. Ethnic groups with a high frequency of HLA-B5 in Asia and America may belong to the same ancestral trunk. The occurrence of Behcet's syndrome in them may be more frequently HLA-B5 positive than in other ethnic groups.

Behcet Syndrome↗