[Current cytogenetic technics and application to the protection of workers].
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Biomedical subjects
Publications and source records attributed to C Laurent.
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Middle-ear effusions of the mucoid type were collected from 14 children with secretory otitis media and analysed by a sensitive assay for hyaluronic acid. The concentration of the polysaccharide varied between three and 42 micrograms/g. in different patients but was in the same range in effusion material taken from the two ears of the same patient. As the hyaluronic acid concentrations were high compared to the serum levels, the results indicate that the effusion material contains a component derived from connective tissue.
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Benign pedunculated tumours of the hypopharynx are very rare. Only a few cases of hypopharyngeal fibrolipomas have been reported. This paper adds 2 more cases with characteristic clinical features. We also present a case of recurrent fibromatous tumours of the hypopharynx with malignant change after 20 years. Malignant transformation of an originally benign hypopharyngeal tumour is extremely unusual. The clinical and pathological aspects of pedunculated benign tumours of the hypopharynx are discussed. Symptoms and signs are few and uncharacteristic. The diagnosis is difficult and often delayed. There is a risk of suffocation by laryngeal obstruction by the tumour. When the accurate diagnosis is established, the treatment of choice should be a lateral pharyngotomy with complete removal of the tumour. Long-term follow-up is recommended.
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