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Biomedical subjects

C L Schepens

Publications and source records attributed to C L Schepens.

At least 55 records · Page 3Linked to original sources
PubMed1987

Stage 5 retinopathy of prematurity. Prognostic value of morphologic findings.

Anterior and posterior segment findings were evaluated in 184 consecutive cases of stage 5 retinopathy of prematurity (ROP) (368 eyes). One hundred seventy patients had one or more examinations under anesthesia and 150 had open-sky vitrectomy (260 eyes) with or without additional surgery. Ocular findings were inspected and special attention was given to verify the morphology of the retinal detachment (RD) as predicted by ultrasonography. Immature iris and/or pupil, posteriorly or totally closed detachment funnels, vascularized epiretinal membranes, retinal folds, tractional retinoschisis, persistent hyaloid system, and subretinal blood and/or organization were the most significant indicators of bad prognosis. Evaluating stage 5 ROP eyes with these variables in mind is therefore essential.

Anterior Eye Segment↗
PubMed1987

Retinopathy of prematurity. The association of a persistent hyaloid artery.

In a review of 160 cases of retinopathy of prematurity (ROP), 14 patients were found to have an associated persistent hyaloid vascular system. The following four different manifestations of a persistent hyaloid system were identified: hyaloid artery anastomosed to peripheral neovascularization (1 case); hyaloid artery present with attached retina (3 cases); fibrous-appearing stalk with detached retina (3 cases); and massive persistent hyaloid vascular system (7 cases). In some cases, the hyaloid artery was only an associated finding and unrelated to ROP. In other cases, the hyaloid artery appeared to be an integral component of the retrolental membrane. Recognition of a massive persistent hyaloid artery has important prognostic value because the vessels are adherent to the retina and the retrolental membrane complicating surgical repair. The role of the associated hyaloid artery in ROP is described.

Humans↗
PubMed1987

Long-term follow-up of photocoagulated choroidal neovascular membranes in age-related macular degeneration.

Eighty-nine consecutive eyes with age-related macular degeneration and choroidal neovascularization treated with green argon laser were followed for an average of 54 months after photocoagulation. Good anatomical and functional results were obtained in 36 of 52 eyes (69%) with foveal new vessels, in 12 of 20 eyes (60%) with juxtafoveal new vessels, and in 13 of 17 eyes (76%) with perifoveal new vessels. Thirty-four of the 89 eyes (38%) had at least one recurrence of new vessels, which most often affected the edge of the previously treated area (30 eyes, 34%). In 18 eyes (20%), these recurrences involved the edge of the scar closer to the fovea.

Aged↗
PubMed1987

Choroidal neovascularization in degenerative myopia: role of laser photocoagulation.

Laser photocoagulation of extrafoveal choroidal new vessels was performed in 19 eyes with degenerative myopia. Sixteen eyes required only one treatment. Three eyes required more than one because of incomplete closure of the new vessels after the first treatment. Choroidal new vessel formation did not recur during the post-treatment follow-up period (average 29.2 months), and a dry, atrophic photocoagulation scar was achieved in all eyes. Visual acuity improved in only two eyes (11%), stabilized in four eyes (21%), and deteriorated in 13 eyes (68%). All except two eyes showed spontaneous progressive enlargement of the atrophic photocoagulation scar, which worsened visual acuity in 13 eyes (68%).

Adult↗
PubMed1986

Role of the vitreous in idiopathic preretinal macular fibrosis.

Of 250 eyes with idiopathic preretinal macular fibrosis, 56 had no posterior vitreous detachment (Group 1), ten had partial posterior vitreous detachments without vitreous traction to the macula (Group 2), 29 had partial posterior vitreous detachments with vitreous traction to the macula (Group 3), and 155 had complete posterior vitreous detachments (Group 4). There were significantly more eyes with visual acuities of 20/60 or worse, cystoid macular changes, or macular fluorescein leakage in Group 3 than in Group 1 or Group 4. Thus, the presence of vitreous traction to the macula was associated with worse anatomic and functional findings.

Adolescent↗
PubMed1986

Self-retaining iris speculum for open-sky vitrectomy.

We have designed a self-retaining iris speculum for use in open-sky vitrectomy. This speculum retracts the iris away from the central field and thus allows the surgeon better visibility and less reliance on an assistant's help for retraction. The possibility of iris laceration and dialysis with excessive bleeding, as sometimes seen with other forms of iris retraction, can be prevented.

Equipment Design↗
PubMed1986

Four-port bimanual vitrectomy.

A further subdivision of functions during vitrectomy surgery has been enabled. By means of a separate, suture-secured fiberoptic endoilluminator and a modified infusion cannula located in the inferior quadrants, two superior sclerotomies are kept free for the use of a variety of simple and complex instruments, alone or in combination. Included among these are vitreous scissors, forceps, picks, spatulas, diathermy probes, and endophotocoagulators.

Humans↗
PubMed1986

Plasma amino acid levels in cataract.

Fasting plasma amino-acid profiles were determined in 32 subjects with either cataractous lenses (24 subjects) or normal lenses (eight subjects). The findings were compared with established laboratory normal values. The amino-acid levels of all subjects with normal lenses were within the normal range for the subjects' age groups. In contrast, subjects with presenile or senile cataracts had markedly elevated levels of glutamine, with similar elevations of alanine in presenile cataract and of histidine in senile cataract. To the best of our knowledge, this is the first report of such a plasma amino-acid pattern in subjects with presenile and senile cataracts.

Adult↗
PubMed1985

Intraocular cysticercosis.

We observed and photographed intraocular cysticercosis in a 50-year-old woman. The subretinal cysticercus in the macular area produced a macular break during its passage from the subretinal space into the vitreous cavity. The parasite was removed by closed vitrectomy, but the macular break was left untreated because there was no vitreous traction to the macula. The patient ultimately developed a subretinal scar in the macular area, and visual acuity improved from hand movements to counting fingers.

Cysticercosis↗
PubMed1985

Photofield mapping in the evaluation and management of subretinal neovascularization.

Photofield mapping is a useful method for classifying subretinal neovascularization based on its area and location. Careful central field mapping is performed to delineate scotomata during evaluation of patients with subretinal new vessels. A photofield map is then constructed by projecting 35 mm fundus photographs and angiograms onto an appropriately-oriented central visual field map. The composite map (photofield) documents the location and relationship of scotomata, subretinal neovascularization, foveal avascular zone, and retinal blood vessels. The areas of subretinal neovascularization and scotomata are measured in square millimeters with a planimeter. The distance between their closest edge and the center of the foveal avascular zone is measured in millimeters. This method permits quantitative comparison of results with different photocoagulation protocols and instrumentation. Such comparative analysis may help improve the technique and instrumentation used in laser photocoagulation of subretinal neovascularization.

Adult↗
PubMed1985

Record form for eye examination under anesthesia.

We designed a record sheet for eye examination under anesthesia, which is often required in children or babies with suspected ocular pathology and in adults with severe mental retardation. The form is both complete and concise, allows for schematic illustrations, and has proven very helpful in more than 200 examinations performed over the past year.

Adult↗