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Biomedical subjects

C L Partain

Publications and source records attributed to C L Partain.

At least 91 records · Page 5Linked to original sources
PubMed1982

Simultaneous bi-plane digital video-fluoroscopy.

A prototype system for digital subtraction angiography that is capable of acquiring digitized video-fluoroscopic images simultaneously from both anterior and lateral imaging chains of a conventional bi-plane system was developed. A hardware module that takes images from both the anterior and lateral video cameras and displays them both on a single video image prior to digitization was designed and constructed. The three-dimensional information provided by a digital bi-plane images should improve the accuracy of cardiac-ventricular function studies. In addition, bi-plane imaging should reduce the need for additional views and the associated repeated injections of contrast media. With this technique, digital bi-plane imaging can be carried out with commercially available systems without duplication of the digital-processing chain.

Animals↗
PubMed1982

Radionuclide ventriculography for assessment of absolute right and left ventricular volumes in children.

We determined absolute right and left ventricular volumes and cardiac output from the equilibrium radionuclide angiogram in 26 children, ages 3 months to 18 years, with diverse types of heart disease. We validated these results by comparing them with left ventricular (20 patients) and right ventricular (16 patients) cineangiographic volumes and cardiac output. Radionuclide volumes and cardiac outputs were determined in two ways: by a geometric method (area-length for left ventricle, Simpson's rule for right ventricle) and by a count-based method (correcting ventricular regional counts for frame duration, acquisition time, venous blood counts and attenuation). Both methods for estimating left ventricular end-diastolic volume compared favorably with cineangiography (correlation coefficients greater than 0.90). The count-based method also correlated well for the right ventricle. End-systolic measurements were not possible. Count-based assessment of cardiac output also correlated well with cineangiographic values. We conclude that right and left ventricular volumes and cardiac output can be reliably measured in children with equilibrium radionuclide ventriculography.

Adolescent↗
PubMed1981

The potential impact of digital radiography (DR) on the speciality of nuclear medicine.

Digital radiography is a reasonably economical system that helps diagnostic imaging physicians to develop increasingly less-invasive procedures, obtain maximal information at a given dose and increase the flexibility and convenience involved with diagnostic workups. The range of applications of DR has not been fully established at this time. Comparison of its properties with those of conventional nuclear medicine may suggest areas of potential application. Compared to nuclear medicine techniques, DR in general provides improved anatomical resolution, improved contrast resolution, sometimes equivalent functional information, and decreased imaging time. On the other hand, some functional nuclear medicine studies provide information not available by DR; including the gallium scan, bone scan, hepatic-biliary scan, and lung scan. Therefore, nuclear medicine procedures will be complimentary in some instances to digital radiography procedures and competitive in others. The proper roles of each modality in various clinical settings await future detailed and comprehensive efficacy studies.

Animals↗
PubMed1980

Ultrasonic-pathologic classification of splenic abnormalities: gray-scale patterns.

In order to more specifically define splenic abnormalities with gray-scale ultrasound, a prospective study was performed involving 40 patients with splenomegaly and/or diseases of the spleen. The following sonographic patterns were found: (a) uniform splenic sonodensity, equal to that of the liver (normal); (b) uniform splenic sonodensity, less than that of the liver (low sonodensity); (c) focal defect, more dense than adjacent spleen (sonodense and sonolucent perisplenic defects. Each pattern was found to be associated with certain pathologic categories, which formed a basis for the ultrasonic-pathologic classification of splenic disease. With the use of these patterns, a more specific diagnosis of splenic abnormalities may be made.

Diagnosis, Differential↗
PubMed1980

Nuclear magnetic resonance and computed tomography: comparison of normal human body images.

Normal human body images of the thorax and abdomen were obtained using nuclear magnetic resonance (NMR) and computed tomography. Correlation of the images allowed precise anatomic identification of organs and structures. Differences between the images appear to be significant. NMR has potential as a methodology for assessing and imaging nuclear composition. Certain clinical implications from this technique are discussed.

Humans↗
PubMed1979

Multiple imaging modalities for the study of pancreatic disease.

Gray scale ultrasonography (US) and computed tomography (CT) have enhanced the role of various imaging modalities in the evaluation of patients with suspected pancreatic disease. When these anatomical studies are normal or equivocal, a functional, radionuclide pancreas scan may be useful. Pancreatic imaging can be achieved using ultrasound, transmission CT, single photon radionuclide imaging, and positron emission CT. A diagnostic imaging decision chart for the evaluation of patients with possible pancreatic disease is useful in choosing the correct imaging modality in a specific situation. Such a chart and its theoretic basis are described in this review. The need to optimize the pancreatic work-up with respect to cost-benefit decisions and diagnostic accuracy, sensitivity, and specificity are of particular concern to the physician. Of all the potential areas for disease, the pancreas has been and remains a particularly difficult diagnostic problem.

Humans↗
PubMed1979

Placenta praevia: significance in the second trimester.

A prospective study was performed on 98 patients to determine the risk of a second trimester placenta praevia remaining until term. The presence and degree of anterior or posterior praevia were scored for each patient. Follow-up data were obtained at delivery on 58 patients. A greater fraction (63.8%) of second trimester praevia was implanted posteriorly. The overall incidence of a second trimester praevia persisting until term was 8.8%.

Female↗
PubMed1979

Cerebral venous angioma: correlation of radionuclide brain scan, transmission computed tomography, and angiography.

Three cases of intracerebral venous angioma, a rare vascular malformation, were studied by radionuclide brain scan, transmission computed tomography (TCT) and angiography. In each case, the radionuclide flow study demonstrated a typical area of abnormal increase in activity during the venous phase; in two of the cases the arterial phase was also abnormal. Each contrast angiogram demonstrated a normal arterial distribution and a characteristic network of abnormal veins that converged to a large transcerebral draining vein. The TCT scans showed enhancing, curvilinear densities; while not specific, this finding should suggest the possibility of venous angioma in the brain.

Adult↗
PubMed1979

The value of the bone scan in idiopathic regional migratory osteoporosis.

Idiopathic regional migratory osteoporosis is a self-limited entity of unknown origin, which has received little attention in the nuclear medicine literature. It is characterized by severe joint pain, typically in a hip, with normal laboratory and normal early radiographic findings. Spontaneous recovery occurs, but recurrence is frequent in another joint, often the opposite hip. Recurrence in the same joint has never been reported. The bone scan is shown to be positive with first symptoms and is important in the diagnosis and management of this entity. Three cases are presented.

Adipose Tissue↗
PubMed1978

Quantitative multiregional CSF kinetics using serial, metrizamide enhanced computed tomography.

Two rhesus monkeys studied by serial metrizamide (Amipaque) enhanced computer tomography (CT) imaging were used to quantitatively analyze cerebrospinal fluid (CSF) kinetics in multiple anatomical regions. Time--density curves were generated for the cisterna magna, suprasellar cistern, quadrigeminal cistern, and sylvian fissure, If clinical, biochemical, and routine static CT scanning indicate a profile suggesting normal pressure hydrocephalus, then CSF kinetics may be quantitatively and dynamically studied by CT imaging with metrizamide enhancement. This multiregional approach may be applied in an attempt to accurately distinguish normal pressure hydrocephalus from cerebral atrophy as a means of predicting which patients will likely profit from surgical diversionary shunting.

Animals↗
PubMed1978

Claw hammer technique for extraction of knives.

A knife deeply imbedded in a patient's shoulder could not be pulled out easily before post-withdrawal angiographic study. The claw of a hammer was placed beneath the hilt of the knife for additional leverage, and the weapon was thereupon successfully removed. The advantage of a post-withdrawal angiogram to assess the degree of extravasation is stressed.

Adult↗
PubMed1978

A multiregional kinetics model for cerebrospinal fluid.

A mathematical model was developed to describe the multiregional flow of intrathecal indium-111 DTPA, and hence indirectly the flow of cerebrospinal fluid, in sequential spinal and cerebral CSF images. The model provides for an arbitrary input function, transport delay between appropriate compartments, transmeningeal and transependymal transport, and for bidirectional flow between most compartments. Two- and eight-compartment models were evaluated. The set of eight nonlinear differential equations was solved using numerical techniques. This model provides a quantitative basis for the interpretation of CSF kinetics.

Adult↗