Pulmonary vascular response to atrial septal defect closure in children.
Explore the source record for details and available documents.
Blood Flow Velocity↗
Biomedical subjects
C L Lucas
Publications and source records attributed to C L Lucas.
Effect of mitral commissurotomy on right-heart work.
Explore the source record for details and available documents.
Adult↗
Analysis of T cell receptor-gene rearrangement in T cells from the cerebrospinal fluid of patients with multiple sclerosis.
Characterization of T cells present in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) may contribute to an understanding of the immunopathologic role of these cells. To analyze the T cells in the CSF of MS patients, 30 cloned T cell lines from each of two MS patients were surveyed for their patterns of T cell receptor (TcR) beta-chain gene rearrangement. DNA from the (CSF-derived) T cell clones was digested with a number of restriction endonucleases and the gene rearrangement patterns were analyzed with a T cell receptor beta-chain probe. Southern blot analysis of the DNA of these T cell clones indicated that all had rearrangements of the TcR beta-chain genes, but none of the rearrangements were identical. These results suggest that, if a few clones of specific T cells are involved, they must form a tiny minority in comparison to the total number of T cells in the CSF of MS patients.
Adult↗
Software analysis of 20 MHz pulsed Doppler quadrature data.
A computer software procedure for processing quadrature data obtained from a 20 MHz pulsed Doppler system is described and the quality of results obtained is illustrated. The system is implemented on a standard laboratory minicomputer system. Software flexibility expands use of this high resolution device for measuring blood velocity to larger vessels than previously demonstrated. Techniques for dealing with high frequency aliasing, time delays, digital filtering and sampling intervals are included.
Animals↗