Immunologic approaches to the control of pseudorabies.
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Biomedical subjects
Publications and source records attributed to C L Kanitz.
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A progressive, fatal spongiform polioencephalopathy was induced in mink intracerebrally inoculated with a suspension of brain from a Suffolk sheep with naturally acquired scrapie. The clinical signs and pathological lesions of the experimental disease were indistinguishable from transmissible mink encephalopathy, a disease of undetermined origin that occurs in mink.
A direct fluorescent antibody (FA) test to demonstrate the presence of Clostridium colinum in cryostat sections of liver and intestine from chickens with ulcerative enteritis ("quail disease") was investigated. Both field cases and experimentally infected birds were studied by FA, bacterial isolation of the clostridium, and histopathology. The FA test proved highly specific for Cl. colinum. It was concluded that the described direct FA procedure offers simplicity and speed over bacterial isolation procedures for etiologic diagnosis of ulcerative enteritis.