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C L Johnson

Publications and source records attributed to C L Johnson.

242 records · Page 14Linked to original sources
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Comparison of human and chimpanzee Kell blood group systems.

Kell antigens on chimpanzee (Pan troglodytes) red cells were determined using specific human alloimmune and murine monoclonal antibodies. After avoidance of interspecies reactions, chimpanzee red cells were found to react with most Kell system antibodies. The chimpanzees had phenotypes similar to those of humans. The main difference was that all of 27 chimpanzee red cell samples tested were of the K:6, -7, phenotype, while in humans most are K:-6, 7. The most common chimpanzee Kell blood group phenotype was K:-1,2,-3,4,5,6,-7,11,12,13,14, 15,18,19,22. Murine monoclonal anti-K2 and -K14 immunoprecipitated a 97-kD protein from chimpanzee red cells and a 93-kD protein from human red cells. Enzymatic deglycosylation yielded proteins of about 79 kD for humans and 77 kD for chimpanzees. Both human and chimpanzee Kell proteins reacted equally well on Western blots with polyclonal rabbit antibody to human Kell protein, which indicated close homology.

Adult↗
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Abstracts to sell.

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Abstracting and Indexing↗
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Bio-Concepts.

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Burns↗
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Posterior compartment fractures of the ankle. A commonly missed athletic injury.

This paper brings to the reader's attention an injury and symptom complex resulting from an ankle sprain during athletic competition. Twenty patients were reviewed and followed over a 3 1/2 year period of time. Three patients presented acutely and 17 patients presented after an extended period of time with residual ankle morbidity. Common to this group of patients was a history of having sustained an ankle sprain, most commonly secondary to a forced plantar flexion type injury. Subsequent disability was generally posterior and postero-lateral ankle pain associated with running and/or jumping. Clinical examination invariably demonstrated posterior ankle pain, particularly with forced plantar flexion of the foot. All patients demonstrated bony changes in the area of the posterior talus and/or tibia by x-ray, and all patients had a positive technetium bone scan of the posterior ankle area. If the injury is diagnosed acutely, cast immobilization is the treatment of choice. If diagnosed late, it is suggested that for those patients who fail conservative treatment, surgical removal of the fragment is best. The majority of patients in this study required surgical extirpation of the posterior talus bony fragment in order to relieve symptoms and return to full sports competition.

Ankle Injuries↗
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Illness and recovery.

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Continuity of Patient Care↗