Pathogenesis of ischaemic pectoral myopathy in the domestic turkey.
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Animals↗
Biomedical subjects
C L Berry
Publications and source records attributed to C L Berry.
Bellmanism: the distortion of reason.
Single-issue compound or class related anxieties about chemical exposures are often the focus of concern for groups that seek to affect the regulatory process itself or the regulatory status of compounds that have passed through it. A characteristic of these groups is an imperfect understanding and use of science, in particular in the evaluation of data. Studies which have been discredited are cited repeatedly and the role of confounding factors is not generally acknowledged. The regulation of medicines, devices, pesticides and some household chemicals depends on the use of a methodology that follows strict protocols. This involves testing in many systems including mammals, other vertebrates, invertebrates, soil macrobiota or ground water, as examples, with often well-defined schemes of interpretation which facilitate extrapolation between species. A complex risk evaluation will then be made for different groups (by age, sex, or occupation, say) or targets (patients, farmers, consumers and vulnerable non-human species). Focusing on an effect in a single group may suggest interventions which will be damaging for others.
Animals↗
Assessing environmental health risks from chemicals.
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Carcinogens↗
Drugs and the developing skeleton.
The skeleton develops from early embryonal stages until the end of the second decade. Normal morphogenesis requires integrated growth, differentiation and morphogenetic movement over prolonged periods of time. The complexity of the processes involved ensures that the potential for drugs to affect the system is very large, and that a number of metabolic pathways may be disturbed. Skeletal abnormalities are thus an important component of many malformation syndromes and are produced by varied genetic mechanisms combined with environmental effects.
Abnormalities, Drug-Induced↗
Practical histopathology class.
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Autopsy↗
The prune belly syndrome--a possible pathogenesis.
Several pathogenetic mechanisms have been suggested to explain the syndrome of deficiency of anterior abdominal muscles and genitourinary abnormalities which is usually seen in males. We have recently seen four such cases, two males and two females, all of which showed obstruction of the lower urinary tract, with dilatation proximally. We wish to suggest that the atrophy of abdominal muscles occurs following venous infarction, due to gross over-distension of the abdomen.
Abdominal Muscles↗