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Biomedical subjects

C Kujat

Publications and source records attributed to C Kujat.

31 records · Page 2Linked to original sources
PubMed1991

[Cerebral MRT in x chromosome linked adrenoleukodystrophy].

Adrenoleukodystrophy (ALD) is a rare lipid storage disease, characterized among other symptoms by a progressive demyelinization of white matter. Changes are well demonstrated by MRT: Leukencephalopathy begins symmetrically in the occipital lobes of the cerebrum and involves furthermore the splenium of the corpus callosum, the nucleus dentatus and the descending tracts. As neurologic signs may precede signs of adrenal insufficiency, MRT may be important to suspect the diagnosis of ALD, which generally is diagnosed by biochemical tests.

Adrenoleukodystrophy↗
PubMed1991

[Erdheim-Chester disease].

Erdheim-Chester disease (ECD) is characterized by lipid granuloma in the long tubular bones, which leads to pathognomonic symmetrical sclerosis of their metaphyses and diaphyses. Lipid granuloma may also be present in numerous other mesenchymal tissues, especially lung, orbit and retroperitoneal space. The clinical course and prognosis of the disease depend on these lesions. Reviewing 30 cases published since 1931 and a personal case with S100 positive cells, we present the typical radiological and clinical findings. There is striking resemblance to chronic disseminated histiocytosis X.

Bone Diseases↗
PubMed1991

[Cerebral manifestations of Erdheim-Chester disease].

Cerebral manifestations of Erdheim-Chester disease are variable, giving a picture like that of multiple sclerosis. White matter lesions are located mainly in cerebellum and pons and lipid granulomas in the meninges. An asymptomatic lesion in the choroid plexus, with prolonged uptake of Gd-DTPA is described for the first time.

Bone Diseases↗
PubMed1991

[Radionuclide cisternography: SPECT- and 3D-technique].

Radionuclide cisternography is indicated in the clinical work-up for hydrocephalus, when searching for CSF leaks, and when testing whether or not intracranial cystic lesions are communicating with the adjacent subarachnoid space. This paper demonstrates the feasibility and diagnostic value of SPECT and subsequent 3D surface rendering in addition to conventional rectilinear CSF imaging in eight patients. Planar images allowed the evaluation of CSF circulation and the detection of CSF fistula. They were advantageous in examinations 48 h after application of 111In-DTPA. SPECT scans, generated 4-24 h after tracer application, were superior in the delineation of basal cisterns, especially in early scans; this was helpful in patients with pooling due to CSF fistula and in cystic lesions near the skull base. A major drawback was the limited image quality of delayed scans, when the SPECT data were degraded by a low count rate. 3D surface rendering was easily feasible from SPECT data and yielded high quality images. The presentation of the spatial distribution of nuclide-contaminated CSF proved especially helpful in the area of the basal cisterns.

Adult↗
PubMed1990

[Medullary carcinoma of the thyroid and 99mTc(V)-DMSA scintigraphy. Clinical results with a new radiopharmaceutical].

99mTc(V)-DMSA scintigraphy is a non-invasive diagnostic tool for diagnostic differentiation and localisation of medullary carcinoma of the thyroid. For primary tumours its sensitivity is 77%. This diagnostic means is not only helpful for the diagnosis of primary tumours, but is especially informative for recidives and metastases of the medullary carcinoma of the thyroid. Its sensitivity for recidives and metastases is 66%. The sensitivity obtained in our study, which included four patients, corresponded to that reported in the literature.

Aged↗
PubMed1983

[Diagnosis of restrictive cardiomyopathy in the hypereosinophilia syndrome by 2-dimensional echocardiography].

The cardiac manifestation of the hypereosinophilic syndrome was diagnosed by means of echocardiography in a 36-year-old man. The following two-dimensional echocardiographic characteristics indicated a restrictive cardiomyopathy in this patient: Enlargement of the left atrium. Thrombotic obliteration of the left ventricle from the apex up to the subvalvular region. Embedding of the chordae tendineae and papillary muscles by the thrombotic mass. Normal left ventricular ejection fraction. The echocardiographic findings were verified by autopsy.

Adult↗