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Biomedical subjects

C Kratz

Publications and source records attributed to C Kratz.

At least 73 records · Page 4Linked to original sources
PubMed1975

[Heart tumors in children. Report of 3 cases with favorable spontaneous courses].

During a 14-year period, 8 cases of primary heart tumours were observed at Sainte-Justine Hospital. Three of these patients had a favourable course without any surgical treatment. The age of these patients was respectively 3 days, 7 weeks and 6 1/2 years. In what concerns the first two patients, the clinical and paraclinical pictures were suggestive of heart disease from the onset. Catheterization and angiocardiography confirmed the presence of a tumour deforming both ventricular cavities. In these two cases, an attempt at surgical resection proved to be impossible in view of the extent of the lesion. Biopsy demonstrated a rhabdomyoma in one of the patients and a diffuse fibroma in the other. Six and four years later, the patients were still alive, and an improvement of both the electrocardiogram and of the cardio-pulmonary X-ray pictures were noted. A second cardiac catheterization showed an almost complete disappearance of the pathological pictures. In what concerns the third patient, he was a 6-year old child with a classical Bourneville's tuberous sclerosis with a localized tumour at the junction of the superior vena cava and the right atrium. Three years later a control catheterization showed the tumour to have remained unchanged. Two conclusions might be drawn from these cases: 1 a surgical operation, although always indicated, should never entail a desperate attempt at tumour removal; 2 the prognosis should never be considered as lethal from the start.

Child, Preschool↗
PubMed1971

Congenital aortic stenosis: follow-up of surgical management.

We have reviewed the cases operated upon for correction of congenital aortic stenosis at l'Hôpital Ste-Justine between 1959 and 1969.Twenty-five of the 26 patients were readmitted for complete clinical, radiological and hemodynamic investigation. Fourteen had a valvular stenosis, eight a diaphragmatic subvalvular lesion, and three had mixed lesions.The results lead us to believe that the surgical treatment of this malformation is justified. The indications for surgery must take into account all available clinical, radiological, electrocardiographic and hemodynamic data.

Adolescent↗
PubMedDate not supplied

Detection of antiphospholipid antibodies in children and adolescents.

The prevalence of antiphospholipid antibodies (APAs) has not yet been studied in children and adolescents with various diseases. We assayed plasma samples of 203 children and adolescents, aged 0.1 to 21 years (median 6 years), by enzyme-linked immunosorbent assay detecting immunoglobulin G (IgG) and IgM antibodies directed against cardiolipin, phosphatidylserine, and phosphatidic acid. According to their diagnosis children were divided into five groups: 10 patients with autoimmune and autoimmune-like diseases (group I); 88 patients with infections (group II); 20 patients with metabolic diseases (group III); 65 children with various other diseases (group IV); 20 healthy children without physical illnes (group V). Results were compared for statistical significance using Fisher's exact test. APAs were found in 65 of 203 patients. In all groups of patients the prevalence of APAs was increased compared with healthy children. The highest prevalence of APAs was found in patients with autoimmune or autoimmune-like diseases or infections. Thrombosis did not occur in children with increased APA levels. In 4 of 65 patients with detectable APAs bleeding was observed. However, three of these four children had additional coagulation abnormalities. We conclude that in children and adolescents increased APA titers may occur in a variety of diseases. The frequency of APA-related symptoms is low.

Adolescent↗
PubMedDate not supplied

Family misfortunes.

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Child↗