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Biomedical subjects

C Keenan

Publications and source records attributed to C Keenan.

43 records · Page 3Linked to original sources
PubMed1971

Doctors' fees.

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Australia↗
PubMedDate not supplied

Thermolabile methylenetetrahydrofolate reductase (C677T): frequency in the Irish population.

BACKGROUND: The genetic variation which underlies the thermolability and low enzyme activity of 5,10-methylenetetrahydrofolate reductase (MTHFR; C677T) has been extensively studied in many populations, including the Irish population. AIM: To describe the examination of the C677T substitution in two new control samples drawn from the Irish population. METHODS: A collection of 487 serum samples was obtained through the blood transfusion services of both the Republic of Ireland and Northern Ireland and a further 115 samples from volunteers. RESULTS: In both samples, the frequency of the thermolabile/low enzyme activity allele (T) was higher than that previously reported for the Irish population. CONCLUSION: This finding thus supports the need for a greater use of internal control/family-based association studies, as opposed to the classic case control study design, when assessing the contribution of the MTHFR T allele to disease processes.

Adult↗
PubMedDate not supplied

Identifying women's descriptions of breast tissue for the promotion of breast self-examination.

The purpose of this study was to identify women's descriptions of their breast tissue. Concrete objective descriptions of the breast, in women's own words, are important to formulate an intervention, based on a self-regulation framework, designed to promote breast self-examination. Descriptions were initially generated from open-ended interviews with 27 women scheduled for mammography. The initial descriptions were validated by an additional 25 women scheduled for mammography. The descriptions of the breast that are relevant to women are presented, conclusions for a subsequent intervention study drawn, and implications for practice addressed.

Adult↗
PubMedDate not supplied

Type of social support among homeless women: its impact on psychosocial resources, health and health behaviors, and use of health services.

BACKGROUND: Information about whether specific types of support are associated with poor psychosocial profiles, health behaviors, and positive use of medical care is critical for identifying homeless women at highest risk for negative outcomes. OBJECTIVES: This study aimed to examine the impact that various levels of support from substance users and nonusers have on homeless women's psychosocial profiles, health and health behaviors, and use of health services. METHODS: This cross-sectional survey used a sample of 1,302 sheltered homeless women. Using controls for potential confounders, outcomes were compared across four mutually exclusive subgroups of women reporting support from substance users only (n = 58), substance nonusers only (n = 439), both users and nonusers (n = 136), and no one (n = 669). Structured and psychometrically sound instruments measured social support, substance use, self-esteem, coping, and psychological symptoms. Additional instruments measured sociodemographic characteristics, sexual risk behavior, health status, and use of health services. RESULTS: As compared with those who have little or no support, women whose support included substance nonusers reported better psychosocial profiles and somewhat greater use of health services. Support from substance nonusers only was associated with better health behaviors and greater use of health services. Support from substance users only was essentially equivalent to not having support. CONCLUSION: Modifying the social networks of homeless women appears to be associated with improved mental health outcomes, less risky health behaviors, and greater use of health services.

Adaptation, Psychological↗