Search PubMed⌕ Search

Biomedical subjects

C Kattamis

Publications and source records attributed to C Kattamis.

At least 109 records · Page 6Linked to original sources

Jaundice and bilirubin levels in Greek children with favism.

Jaundice and bilirubin levels varied widely in 85 children with favism. Low bilirubin levels (less than 2 mg/100 ml) with clinically undetectable jaundice were seen in 34 (40%), mild jaundice in 32 (38%), moderate in 16 (19%), and severe (greater than 8 mg/100 ml) in 3 (4%). Bilirubin levels were unrelated to the severity of anaemia or to reticulocytosis. The absence of bilirubinaemia and jaundice in a high proportion of the patients was attributed to the ability of the liver to conjugate large amounts of bilirubin. The extreme bilirubinaemia and jaundice observed in a minority of cases was attributed to the existence of an additional hereditary factor affecting the liver.

Bilirubin↗

Brucellosis in two thalassaemic patients infected by blood transfusions from the same donor.

Brucellosis was diagnosed in two polytransfused, thalassaemic patients who had received blood containing brucella agglutinins from an asymptomatic donor. In one of the patients the onset of the disease simulated infectious mononucleosis. Despite the fact that both cases were splenetomized, the course of illness was not life threatening. However, a tendency for recurrence of the infection and persistence of high brucella agglutinin titres were noted.

Adolescent↗

Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.

Twenty-five infants with generalized seborrhoeic dermatitis have been studied with reference to the provision of optimum treatment. Leucocyte counts and chest x-ray examination are recommended in every case. Irrespective of clinical findings, antibiotics should be given to patients with overt bacterial infection and those with leucocytosis, shift to the left, and toxic granulation. One group of infants was treated with vitamin B complex plus biotin given slowly intravenously over 24 hours; a second group was given only biotin intravenously over 2-3 hours; and a third group only biotin over 1-2 minutes. A fourth group was treated with both biotin and antibiotics for confirmed or suspected superimposed bacterial infection. The results were excellent in all groups. Skin lesions improved within 4-8 days and cleared completely within 15-30 days. Intravenous administration of biotin is recommended as less painful and less dangerous than multiple intramuscular injections.

Biotin↗

Validity of a screening test for typing serum cholinesterase variants among Greek populations.

A screening method for determining the abnormal phenotypes of human serum cholinesterase variants in a population survey was investigated. The test appeared to be satisfactory in detecting abnormal genotypes, but not assigning them into correct classification. The results of the population survey indicate that there may be a higher frequency of ChU1ChD1 genotype than those reported earlier. Family studies of the suxamethonium-sensitive propositi in this population demonstrate that abnormal genes ChD1, ChF1 and ChS1 are segregating, according to the usual Mendelian type of inheritance pattern. The possibility of a relatively high frequency of these abnormal genotypes among the Greek population has been indicated.

Cholinesterases↗